一般描述
Factor V, a glycoprotein is usually seen in the alpha granules of platelets and in plasma.
Factor Va is the activated form of factor V and the cofactor of Xa. It is a component of the prothrombinase complex.
生化/生理作用
Factor V is a key component in blood coagulation systems, where deficiencies can inhibit thrombin generation and affect hemostasis. It has been used in studies of coagulopathic bleeding which occurs following injury and is a leading cause of hospital deaths.
Factor Va serves as a receptor and positive effector of factor Xa. Hence it can efficiently help in the conversion of prothrombin to thrombin.
联系
View this factors role in the Coagulation Cascade
单位定义
One unit is equivalent to the Factor V activity in 1.0 mL of normal human plasma at pH 7.4 at 37 °C.
外形
Aqueous solution containing 50% (v/v) glycerol and 5mM CaCl2
免责声明
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持