生物来源
mouse
偶联物
unconjugated
抗体形式
ascites fluid
抗体产品类型
primary antibodies
克隆
FIL-7B10, monoclonal
分子量
antigen 115 kDa
包含
15 mM sodium azide
种属反应性
bovine, sheep, human
请勿与下列物质发生反应
mouse, chicken, rat
技术
immunohistochemistry (frozen sections): suitable
indirect immunofluorescence: 1:400 using bovine lens frozen sections
microarray: suitable
western blot: suitable
同位素/亚型
IgG1
UniProt登记号
运输
dry ice
储存温度
−20°C
基因信息
human ... BFSP1(631)
免疫原
human and bovine lens filament enriched fraction (plasma membrane-cytoskeleton complex).
应用
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
Western Blotting (1 paper)
生化/生理作用
The antibody recognizes an epitope located within either the rod or the N-terminal non-(α) helical domain of the filensin molecule. May be used in immunoblotting where it specifically detects both the full-length filensin (115 kDa), the processed fragment, and a variety of breakdown products in the mol. wt. range of 28-69 kDa. Does not react with cultured lens epithelial cells nor with normal human skin, psoriatic or tumoral skin (basal cell carcinoma).
未找到合适的产品？
试试我们的产品选型工具.
法规信息
新产品
此项目有
Shih-Ping Su et al.
Molecular vision, 17, 2798-2807 (2012-01-06)
It is well established that levels of soluble α-crystallin in the lens cytoplasm fall steadily with age, accompanied by a corresponding increase in the amount of membrane-bound α-crystallin. Less well understood, is the mechanism driving this age-dependent membrane association. The
A Sandilands et al.
European journal of cell biology, 67(3), 238-253 (1995-07-01)
Filensin is a lens-specific intermediate filament protein, expressed in the lens fiber cells but not the lens epithelium. Using antibodies to filensin and the other lens intermediate filament proteins, vimentin and CP49, the codistribution of filensin with CP49 and independence
Shih-Ping Su et al.
Biochimica et biophysica acta, 1814(5), 647-656 (2011-03-31)
The optical properties of the lens are dependent upon the integrity of proteins within the fiber cells. During aging, crystallins, the major intra-cellular structural proteins of the lens, aggregate and become water-insoluble. Modifications to crystallins and the lens intermediate filaments
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持