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F7131

N- [3-（2-呋喃基）丙烯酰基]-Phe - 双甘氨酸

Name: N- [3-（2-呋喃基）丙烯酰基]-Phe - 双甘氨酸
Brand: SIGMA

chromogenic, ≥99% (HPLC)

别名:

FAPGG, N-[3-（2-呋喃基）丙烯酰基]- L -苯丙氨酰-甘氨酰-甘氨酸

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关于此项目

经验公式（希尔记法）:

C₂₀H₂₁N₃O₆

化学文摘社编号:

64967-39-1

分子量:

399.40

UNSPSC Code:

12352202

PubChem Substance ID:

24894929

NACRES:

NA.32

MDL number:

MFCD00036816

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属性

产品名称

N- [3-（2-呋喃基）丙烯酰基]-Phe - 双甘氨酸,

Quality Level

300

storage temp.

−20°C

SMILES string

OC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)\C=C\c2ccco2

InChI

1S/C20H21N3O6/c24-17(9-8-15-7-4-10-29-15)23-16(11-14-5-2-1-3-6-14)20(28)22-12-18(25)21-13-19(26)27/h1-10,16H,11-13H2,(H,21,25)(H,22,28)(H,23,24)(H,26,27)/b9-8+/t16-/m0/s1

InChI key

ZDLZKMDMBBMJLI-FDMDGMSGSA-N

Gene Information

human ... ACE(1636), ACE2(59272)
mouse ... ACE3(217246)
rat ... ACE(11421), ACE2(70008), ACE3(498012)

说明

General description

N-[3-（2-呋喃基）丙烯酰基]-Phe-Gly-Gly 作为血管紧张素转化酶 (ACE) 的底物，用于 ACE 的抑制试验。

连续分光光度法测定血管紧张素转化酶 (ACE) 的底物。

Application

N-[3-（2-呋喃基）丙烯酰基] 苯基-Gly-Gly 已用于 ACE（血管紧张素转化酶）抑制活性的动力学分光光度法测定。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Assessment and optimization of kinetic methods for angiotensin-converting enzyme in plasma.

J E Buttery et al.

Clinical chemistry, 39(2), 312-316 (1993-02-01)

In the kinetic angiotensin-converting enzyme (ACE) method, a practical and optimal buffer is 80 mmol/L borate buffer at pH 8.2 (37 degrees C). A lag phase is detected in the reaction, and a 5-min incubation of substrate and plasma is

Antioxidant peptides with Angiotensin converting enzyme inhibitory activities and applications for Angiotensin converting enzyme purification.

Wen-Chi Hou et al.

Journal of agricultural and food chemistry, 51(6), 1706-1709 (2003-03-06)

Five commercial peptides, namely, reduced glutathione (GSH), oxidized glutathione (GSSG), carnosine, homocarnosine, and anserine, were used to test angiotensin converting enzyme inhibitory (ACEI) activities using N-[3-(2-furyl)acryloyl]-Phe-Gly-Gly (FAPGG) as a substrate. All of these peptides showed dose-dependent ACEI activities. Using 50%

Preparation and Identification of ACE Inhibitory Peptides from the Marine Macroalga Ulva intestinalis.

Siqi Sun et al.

Marine drugs, 17(3) (2019-03-22)

Angiotensin I-converting enzyme (ACE) inhibitory peptides derived from seaweed represent a potential source of new antihypertensive. The aim of this study was to isolate and purify ACE inhibitory peptides (ACEIPs) from the protein hydrolysate of the marine macroalga Ulva intestinalis.

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全球贸易项目编号

货号	GTIN
F7131-25MG	04061833619308
F7131-500MG	04061833619315
F7131-100MG	04061833619292