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F7131

N- [3-（2-呋喃基）丙烯酰基]-Phe - 双甘氨酸

Name: N- [3-（2-呋喃基）丙烯酰基]-Phe - 双甘氨酸
Brand: SIGMA

chromogenic, ≥99% (HPLC)

别名:

FAPGG, N-[3-（2-呋喃基）丙烯酰基]- L -苯丙氨酰-甘氨酰-甘氨酸

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关于此项目

经验公式（希尔记法）:

C₂₀H₂₁N₃O₆

化学文摘社编号:

64967-39-1

分子量:

399.40

UNSPSC Code:

12352202

PubChem Substance ID:

24894929

NACRES:

NA.32

MDL number:

MFCD00036816

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产品名称

N- [3-（2-呋喃基）丙烯酰基]-Phe - 双甘氨酸,

Quality Level

300

storage temp.

−20°C

SMILES string

OC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)\C=C\c2ccco2

InChI

1S/C20H21N3O6/c24-17(9-8-15-7-4-10-29-15)23-16(11-14-5-2-1-3-6-14)20(28)22-12-18(25)21-13-19(26)27/h1-10,16H,11-13H2,(H,21,25)(H,22,28)(H,23,24)(H,26,27)/b9-8+/t16-/m0/s1

InChI key

ZDLZKMDMBBMJLI-FDMDGMSGSA-N

Gene Information

human ... ACE(1636), ACE2(59272)
mouse ... ACE3(217246)
rat ... ACE(11421), ACE2(70008), ACE3(498012)

General description

N-[3-（2-呋喃基）丙烯酰基]-Phe-Gly-Gly 作为血管紧张素转化酶 (ACE) 的底物，用于 ACE 的抑制试验。

连续分光光度法测定血管紧张素转化酶 (ACE) 的底物。

Application

N-[3-（2-呋喃基）丙烯酰基] 苯基-Gly-Gly 已用于 ACE（血管紧张素转化酶）抑制活性的动力学分光光度法测定。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

0000496556

0000413886

0000413887

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Assessment and optimization of kinetic methods for angiotensin-converting enzyme in plasma.

J E Buttery et al.

Clinical chemistry, 39(2), 312-316 (1993-02-01)

In the kinetic angiotensin-converting enzyme (ACE) method, a practical and optimal buffer is 80 mmol/L borate buffer at pH 8.2 (37 degrees C). A lag phase is detected in the reaction, and a 5-min incubation of substrate and plasma is

Antioxidant peptides with Angiotensin converting enzyme inhibitory activities and applications for Angiotensin converting enzyme purification.

Wen-Chi Hou et al.

Journal of agricultural and food chemistry, 51(6), 1706-1709 (2003-03-06)

Five commercial peptides, namely, reduced glutathione (GSH), oxidized glutathione (GSSG), carnosine, homocarnosine, and anserine, were used to test angiotensin converting enzyme inhibitory (ACEI) activities using N-[3-(2-furyl)acryloyl]-Phe-Gly-Gly (FAPGG) as a substrate. All of these peptides showed dose-dependent ACEI activities. Using 50%

Preparation and Identification of ACE Inhibitory Peptides from the Marine Macroalga Ulva intestinalis.

Siqi Sun et al.

Marine drugs, 17(3) (2019-03-22)

Angiotensin I-converting enzyme (ACE) inhibitory peptides derived from seaweed represent a potential source of new antihypertensive. The aim of this study was to isolate and purify ACE inhibitory peptides (ACEIPs) from the protein hydrolysate of the marine macroalga Ulva intestinalis.

Automated kinetic determination of angiotensin-converting enzyme in serum.

A Harjanne

Clinical chemistry, 30(6), 901-902 (1984-06-01)

In this automated kinetic modification of a previous method (Anal Biochem 95: 540-548, 1979) for determining angiotensin-converting enzyme (EC 3.4.15.1), 3-(2- furylacryloyl )-L- phenylalanylglycylglycine is used as the substrate. The change in absorbance at 340 nm is used to monitor

Evaluation of anti-hypertensive activity of Ulmus wallichiana extract and fraction in SHR, DOCA-salt- and L-NAME-induced hypertensive rats.

Anees A Syed et al.

Journal of ethnopharmacology, 193, 555-565 (2016-10-11)

Ulmus wallichiana Planchon (Himalayan Elm), a traditional medicinal plant, used in fracture healing in folk tradition of Uttarakhand, Himalaya, India. It is also used as diuretic. U. rhynchophylla, native to China, known as Gou Teng in Chinese medicine, is used

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全球贸易项目编号

货号	GTIN
F7131-25MG	04061833619308
F7131-500MG	04061833619315
F7131-100MG	04061833619292

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