Anti-Glutamate Receptor NMDAR1 (NR1) (Splice Variant Insert C2′) antibody produced in rabbit

synthetic peptide representing the sequence of the C2′ splice variant.

Anti-Glutamate Receptor NMDAR1 (NR1) (Splice Variant Insert C2′) antibody is suitable for immunoprecipitation at a dilution of 1:200 and western blot at a dilution of 1:1000 using rat and mouse brain homogenates and HEK 293 cells.

NMDA receptors (NMDAR) are glutamate-gated ion channels. It is sensitive to N-methyl-D-aspartate (NMDA) and consists of several homologous subunits (NMDAR1). NMDAR is highly expressed in the central nervous system and involved in excitatory synaptic transmission as well as synaptic plasticity. The activity of NMDA receptors are modulated by glycine. It exhibits high calcium permeability and unique voltage-dependent sensitivity to magnesium. It has been reported that phosphorylated NMDA receptors may regulate their function and play a role in many forms of synaptic plasticity such as long-term potentiation.

Lyophilized powder from 5 mM ammonium bicarbonate (some residual salt may be present)

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.