G3127
Gly-Sar
≥98% (TLC)
别名:
甘氨酰肌氨酸
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关于此项目
线性分子式:
NH2CH2CON(CH3)CH2COOH
CAS Number:
分子量:
146.14
Beilstein:
1768450
EC 号:
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.26
Product Name
Gly-Sar,
方案
≥98% (TLC)
质量水平
表单
powder
颜色
white
mp
198 °C
储存温度
−20°C
SMILES字符串
CN(CC(O)=O)C(=O)CN
InChI
1S/C5H10N2O3/c1-7(3-5(9)10)4(8)2-6/h2-3,6H2,1H3,(H,9,10)
InChI key
VYAMLSCELQQRAE-UHFFFAOYSA-N
基因信息
human ... SLC15A1(6564)
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相关类别
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Jinling Wang et al.
International journal of nanomedicine, 13, 7997-8012 (2018-12-13)
Polymeric micelles (PMs) hold promise for improving solubility and oral absorption of poorly soluble drugs. Unfortunately, the oral absorption of PMs is also limited by intestinal epithelium. To improve the oral delivery efficiency of micelles, transporter-mediated micelles could enhance the
Hovhannes J Gukasyan et al.
Pharmaceutical research, 34(12), 2488-2497 (2017-08-24)
Studies were conducted in primary cultured rat alveolar epithelial cell monolayers to characterize peptide transporter expression and function. Freshly isolated rat lung alveolar epithelial cells were purified and cultured on permeable support with and without keratinocyte growth factor (KGF). Messenger
Beta- and gamma-di- and tripeptides as potential substrates for the oligopeptide transporter hPepT1.
Ina Hubatsch et al.
Journal of medicinal chemistry, 50(21), 5238-5242 (2007-09-25)
The hPepT1-mediated transport properties of a series of 11 synthesized beta- and gamma-peptides have been studied in Caco-2 cells. The results show that several of the compounds interact with the peptide transporter, but only two beta-dipeptides act as substrates and
Junji Miyabe et al.
Journal of pharmacological sciences, 139(3), 215-222 (2019-03-06)
Boron neutron capture therapy (BNCT) is a radiotherapy utilizing the neutron capture and nuclear fission reaction of 10B taken up into tumor cells. The most commonly used boron agent in BNCT, p-borono-l-phenylalanine (BPA), is accumulated in tumors by amino acid
Jian Cang et al.
Drug metabolism and pharmacokinetics, 25(5), 500-507 (2010-09-30)
To investigate the pharmacokinetics and mechanism of intestinal absorption of JBP485 in rats, the pharmacokinetics of JBP485 were investigated in vivo both intravenously and orally. The effects of glycylsarcosine (Gly-Sar) on the uptake and transepithelial transport of JBP485 were examined
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