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Merck
CN

G6878

Sigma-Aldrich

胍基丙酸

≥97.5% (TLC)

别名:

β——胍基丙酸

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关于此项目

线性分子式:
HN=C(NH2)NHCH2CH2COOH
化学文摘社编号:
分子量:
131.13
Beilstein:
1705262
EC 号:
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.26
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产品名称

胍基丙酸,

方案

≥97.5% (TLC)

表单

powder or crystals

颜色

white

mp

222 °C (dec.) (lit.)

储存温度

2-8°C

SMILES字符串

NC(=N)NCCC(O)=O

InChI

1S/C4H9N3O2/c5-4(6)7-2-1-3(8)9/h1-2H2,(H,8,9)(H4,5,6,7)

InChI key

KMXXSJLYVJEBHI-UHFFFAOYSA-N

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生化/生理作用

研究了β-胍基丙酸作为类似于 L-精氨酸的抗聚集分子在蛋白质复性过程中的潜在用途。β-胍基丙酸可用于研究其对促进伤口愈合的内皮细胞的增殖活性。β-胍基丙酸与瘦素关系密切。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Pflugers Archiv : European journal of physiology, 452(3), 342-348 (2006-02-24)
There has been speculation on the origin of the increased endurance of skeletal muscles in creatine kinase (CK)-deficient mice. Important factors that have been raised include the documented increased mitochondrial capacity and alterations in myosin heavy chain (MyHC) isoform composition
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Neurobiology of disease, 43(1), 152-162 (2011-03-17)
Guanidinopropionic acid (GPA) increases AMPK activity, mitochondrial function and biogenesis in muscle and improves physiological function, for example during aging. Mitochondrial dysfunction is a major contributor to the pathogenesis of Parkinson's disease. Here we tested whether GPA prevents neurodegeneration of
M García-Delgado et al.
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Creatine plays a role in energy storage and transport/shuttle of high-energy phosphate in heart, brain, retina, testis and skeletal muscle. These tissues take creatine from the plasma via a 2Na(+)/1Cl(-)/1creatine cotransporter (CRT). We have previously demonstrated that renal apical membrane
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Neurochemical research, 34(10), 1704-1711 (2009-04-24)
GABA(C) receptors play a role in myopia, memory-related disorders and circadian rhythms signifying a need to develop potent and selective agents for this class of receptors. Guanidino analogs related to glycine, beta-alanine and taurine were evaluated at human rho(1)GABA(C) receptors

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