G6878
胍基丙酸
≥97.5% (TLC)
别名:
β——胍基丙酸
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关于此项目
线性分子式:
HN=C(NH2)NHCH2CH2COOH
化学文摘社编号:
分子量:
131.13
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
206-530-0
MDL number:
Beilstein/REAXYS Number:
1705262
产品名称
胍基丙酸,
InChI key
KMXXSJLYVJEBHI-UHFFFAOYSA-N
InChI
1S/C4H9N3O2/c5-4(6)7-2-1-3(8)9/h1-2H2,(H,8,9)(H4,5,6,7)
SMILES string
NC(=N)NCCC(O)=O
assay
≥97.5% (TLC)
form
powder or crystals
color
white
mp
222 °C (dec.) (lit.)
storage temp.
2-8°C
Quality Level
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Biochem/physiol Actions
研究了β-胍基丙酸作为类似于 L-精氨酸的抗聚集分子在蛋白质复性过程中的潜在用途。β-胍基丙酸可用于研究其对促进伤口愈合的内皮细胞的增殖活性。β-胍基丙酸与瘦素关系密切。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Efraim H Rosenberg et al.
Journal of inherited metabolic disease, 29(2-3), 345-346 (2006-06-10)
In the study reported, we prove that mutations in the SLC6A8 gene are responsible for SLC6A8 deficiency, a cerebral creatine deficiency syndrome (CCDS), since overexpression of the wild-type SLC6A8 open reading frame (ORF) restores the creatine uptake profile in SLC6A8-deficient
Mary Chebib et al.
Neurochemical research, 34(10), 1704-1711 (2009-04-24)
GABA(C) receptors play a role in myopia, memory-related disorders and circadian rhythms signifying a need to develop potent and selective agents for this class of receptors. Guanidino analogs related to glycine, beta-alanine and taurine were evaluated at human rho(1)GABA(C) receptors
A Bexfield et al.
The British journal of dermatology, 162(3), 554-562 (2009-10-06)
Maggot therapy, utilizing the larvae of Lucilia sericata, has been reported to reduce the bacterial load within wounds and also to enhance wound healing. Maggot excretions/secretions (ES) have been shown to have a role in the success of maggot therapy.
Inge Oudman et al.
PloS one, 8(1), e52879-e52879 (2013-01-18)
Creatine kinase plays a key role in cellular energy transport. The enzyme transfers high-energy phosphoryl groups from mitochondria to subcellular sites of ATP hydrolysis, where it buffers ADP concentration by catalyzing the reversible transfer of the high-energy phosphate moiety (P)
Shirin Mirshamsi et al.
Regulatory peptides, 141(1-3), 19-24 (2007-03-10)
A number of hormones, including leptin, have been shown to inhibit food intake in humans and animals. Analogues of 3-guanidinopropionic acid have also been found to reduce total food intake, but their mechanisms of action have not been well studied.
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