Anti-GRO1 antibody produced in chicken

Immunogen Sequence: GI # 4504153, sequence 35-107

Recombinant chemokine (C-X-C motif) ligand 1

Anti-GRO1 antibody produced in chicken is suitable for indirect ELISA and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

The chemokine (C-X-C motif) ligand 1 (CXCL1) is a protein encoded by the CXCL1 gene in humans and belongs to CXC chemokine family (earlier called as called GRO1 oncogene). It is a cytokine with inflammatory and growth-regulatory properties for melanoma growth-stimulatory activity. CXCL1 is a ligand for CXC chemokine receptor 2 that is expressed on hepatic stellate cells (HSC). It contributes to HSC activation and fibrogenesis. CXCL1 may regulate tumor epithelial-stromal interactions that facilitate tumor growth and invasion. It may be assoiated with bladder carcinogenesis and progression. CXCL1 expression in epithelial cells and its secretion induces angiogenesis. It serves as a target for the embryo′s secretion product IL-1β in decidualised endometrial stromal cells during the peri-implantation period.

Solution in phosphate buffered saline containing 0.02% sodium azide.

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