生物来源
chicken
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
种属反应性
rat, human, mouse
制造商/商品名称
Genway 15-288-22788A
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
基因信息
human ... TLR3(7098)
一般描述
Toll-like receptor 3 (TLR3) is a protein encoded by the TLR3 gene in humans. It is a member of the Toll-like receptor family localized in various intracellular structures such as endosomes and endoplasmic reticulum.
应用
Anti-TLR3 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
生化/生理作用
Toll-like receptor 3 (TLR3) is mainly involved in both the innate and adaptive immune systems. TLR3 activation in the skin induces inflammation and increases the expression of genes involved in skin barrier repair while TLR2 activation prevents excessive inflammation by blocking downstream TLR3 signaling.
外形
Solution in phosphate buffered saline containing 0.02% sodium azide.
未找到合适的产品？
试试我们的产品选型工具.
储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
此项目有
Andrew W Borkowski et al.
The Journal of investigative dermatology, 134(9), 2315-2320 (2014-05-03)
UV radiation poses a significant risk to human health. The mechanisms that help repair UV-damaged cells have recently been more clearly defined with the observation that Toll-like receptor 3 can sense self RNA released from necrotic keratinocytes following UV damage.
Regina Vontell et al.
Journal of neuropathology and experimental neurology, 74(3), 273-285 (2015-02-11)
Toll-like receptor-3 (TLR3) has been identified in a variety of intracellular structures (e.g. endosomes and endoplasmic reticulum); it detects viral molecular patterns and damage-associated molecular patterns. We hypothesized that, after white matter injury (WMI) has occurred, localization and activation of
Konstantin S Mineev et al.
FEBS letters, 588(21), 3802-3807 (2014-09-15)
Toll-like receptors (TLRs) take part in both the innate and adaptive immune systems. The role of the transmembrane domain in TLR signaling is still elusive, while its importance for the TLR activation was clearly demonstrated. In the present study the
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持