生物来源
chicken
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
种属反应性
mouse, human, rat
制造商/商品名称
Genway 15-288-22898
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... RGS17(26575)
免疫原
Immunogen Sequence: GI # 21361405, sequence 41-100
Recombinant regulator of G-protein signalling 17
应用
Anti-RGS17 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
生化/生理作用
Regulator of G-protein signaling 17 is a protein encoded by the RGS17 gene in humans and is mapped to chromosome 6q23-25. RGS17 encodes a member of the regulator of G-protein signaling RGS-Rz subfamily. It is differentially expressed in hepatocellular carcinoma (HCC) and plays a central role in regulating transformed hepatocyte tumorgenicity. RGS17 is over-expressed in human lung adenocarcinomas and plays an important role in lung tumor growth.
外形
Solution in phosphate buffered saline containing 0.02% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
此项目有
Eugene Sokolov et al.
Cellular signalling, 23(10), 1603-1610 (2011-05-31)
Guanine nucleotide regulatory proteins (G-proteins) are central to normal hepatocyte function and are implicated in hepatic disease initiation and progression. Regulators of G-protein signaling (RGS) are critical to defining G-protein-dependent signal fidelity, yet the role of RGS proteins in the
Ming You et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 15(8), 2666-2674 (2009-04-09)
We have previously mapped a major susceptibility locus influencing familial lung cancer risk to chromosome 6q23-25. However, the causal gene at this locus remains undetermined. In this study, we further refined this locus to identify a single candidate gene, by
Huiping Zhang et al.
Behavioral and brain functions : BBF, 8, 23-23 (2012-05-18)
RGS17 and RGS20 encode two members of the regulator of G-protein signaling RGS-Rz subfamily. Variation in these genes may alter their transcription and thereby influence the function of G protein-coupled receptors, including opioid receptors, and modify risk for substance dependence.
Yihua Sun et al.
Biochemical and biophysical research communications, 396(2), 501-507 (2010-04-28)
Lung cancer is one of the most devastating diseases worldwide. RGS17 is previously shown to be over-expressed in human lung adenocarcinomas and plays an important role in lung tumor growth. Here we have identified a miRNA, has-mir-182, involved in the
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