H2519
肝素酶 I 来源于肝素黄杆菌
Lyophilized powder stabilized with approx. 25% bovine serum albumin, ≥200 units/mg protein (enzyme + BSA)
别名:
肝素裂解酶I, 肝素酶
应用
来自肝素黄杆菌（Flavobacterium heparinum）的肝素酶I已被用于：
- 消化血浆样品
- 研究培养基、洗涤和超声处理对肺炎衣原体(Chlamydia pneumonia)感染性的影响
- 酶法去除人横纹肌肉瘤细胞表面的硫酸乙酰肝素
生化/生理作用
来自肝素黄杆菌（Flavobacterium heparinum）的肝素酶I通过裂解肝素AT III结合位点处的α-糖苷键而发挥作用。这就产生了小的寡糖碎片。肝素酶 I 可以中和蛋白质的抗凝作用。肝素酶I的半衰期为15-18分钟。
其他说明
在25 °C、pH 7.5条件下，一个单位（Sigma单位）每小时可形成0.1 μ摩尔不饱和糖醛酸。一个国际单位（I.U.）相当于大约600个Sigma单位。
警示用语：
Danger
危险声明
预防措施声明
危险分类
Resp. Sens. 1
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
低风险生物材料
此项目有
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Cardiopulmonary Bypass: Principles and Practice, 509-509 (2008)
Wataru Hashimoto et al.
Biochemistry, 53(4), 777-786 (2014-01-21)
Pedobacter heparinus (formerly known as Flavobacterium heparinum) is a typical glycosaminoglycan-degrading bacterium that produces three heparin lyases, Hep I, Hep II, and Hep III, which act on heparins with 1,4-glycoside bonds between uronate and amino sugar residues. Being different from
HeparinHeparin - A Century of Progress, 273-273 (2012)
Methodological aspects affecting the infectivity of Chlamydia pneumoniae in cell cultures in vitro
Yan Y, et al.
Journal of Microbiological Methods, 61(1), 127-130 (2005)
Differential expression of plasma microRNA in preeclamptic patients at delivery and 1 year postpartum
Murphy MSQ, et al.
American Journal of Obstetrics and Gynecology, 213(3), 367-e1-367-e1 (2015)
商品
Uncover more about glycosaminoglycans and proteoglycans including the structure of glycosaminoglycans (GAGs), the different types of GAGs, and their functions.
Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units.
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