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Merck
CN

H4024

L-Homocysteinesulfinic acid

≥98% (TLC)

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关于此项目

经验公式(希尔记法):
C4H9NO4S
化学文摘社编号:
分子量:
167.18
UNSPSC Code:
12352202
PubChem Substance ID:
MDL number:
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assay

≥98% (TLC)

storage temp.

−20°C

SMILES string

NC(CCS(O)=O)C(O)=O

InChI

1S/C4H9NO4S/c5-3(4(6)7)1-2-10(8)9/h3H,1-2,5H2,(H,6,7)(H,8,9)

InChI key

PDNJLMZEGXHSCU-UHFFFAOYSA-N

Biochem/physiol Actions

Neurotransmitter candidate


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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分析证书(COA)

Lot/Batch Number

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G A Thompson et al.
Neuropharmacology, 34(8), 857-863 (1995-08-01)
Depolarizations induced by a range of amino acids including some sulphur-containing excitatory transmitter candidates were evoked from motoneurones in the neonatal rat spinal cord under conditions that precluded activation of known ionotropic glutamate receptors. The responses could be partially and
Philipp Görtz et al.
Journal of the neurological sciences, 218(1-2), 109-114 (2004-02-05)
Severe hyperhomocysteinemia (50-200 microM) often presents itself with acute neuronal dysfunction including seizures and psychosis. Its moderate form (15-50 microM) is associated with cognitive impairment and dementia. We investigated the neuropharmacological effects of homocysteine and its oxidized forms, homocysteinesulfinic acid
A Becker et al.
International journal of clinical pharmacology and therapeutics, 45(9), 504-515 (2007-10-03)
Interference of methotrexate (MTX) with the metabolism of homocysteine may contribute to MTX neurotoxicity. In this pilot study we measured the concentration of homocysteine and related metabolites in the cerebrospinal fluid (CSF) of patients with primary central nervous system lymphoma