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Merck
CN

H6012

4-Hydroxyestrone

≥90% (HPLC)

别名:

1,3,5(10)-Estratriene-3,4-diol-17-one

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关于此项目

经验公式(希尔记法):
C18H22O3
化学文摘社编号:
分子量:
286.37
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
Assay:
≥90% (HPLC)
Form:
powder
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sterility

non-sterile

Quality Segment

assay

≥90% (HPLC)

form

powder

solubility

methanol: 10 mg/mL, clear, colorless to faintly brownish-yellow

shipped in

ambient

storage temp.

−20°C

SMILES string

[H][C@]12CC[C@]3(C)C(=O)CC[C@@]3([H])[C@]1([H])CCc4c(O)c(O)ccc24

InChI

1S/C18H22O3/c1-18-9-8-11-10-4-6-15(19)17(21)13(10)3-2-12(11)14(18)5-7-16(18)20/h4,6,11-12,14,19,21H,2-3,5,7-9H2,1H3/t11-,12-,14+,18+/m1/s1

InChI key

XQZVQQZZOVBNLU-QDTBLXIISA-N

Biochem/physiol Actions

4-Hydroxyestrone is an endogenous estrogen metabolite, which exhibits a strong neuroprotective effect against oxidative damage. It also provides effective protection against kanic acid-induced hippocampal oxidative damage in rats when compared to 17β-estradiol. 4-Hydroxyestrone regulates the angiogenic process during corpus luteum formation. It might be involved in an increased risk of cancer. 4-Hydroxyestrone is found in the early and mid-luteal phases.


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

199.9 °F - closed cup

flash_point_c

93.3 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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Lot/Batch Number

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全球贸易项目编号

货号GTIN
H6012-25MG04061832850467
H6012-5MG04061832856629