H9633
L-同型半胱氨酸
≥98% (TLC)
别名:
L-2-氨基-4-磺基丁酸
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C4H9NO5S
化学文摘社编号:
分子量:
183.18
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.32
MDL number:
产品名称
L-同型半胱氨酸, ≥95%
SMILES string
N[C@@H](CCS(O)(=O)=O)C(O)=O
InChI
1S/C4H9NO5S/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H,8,9,10)/t3-/m0/s1
InChI key
VBOQYPQEPHKASR-VKHMYHEASA-N
assay
≥95%
≥98% (TLC)
form
powder
color
white to off-white
application(s)
cell analysis
Quality Level
Application
L-同型半胱氨酸已被用于研究在神经系统中过氧化氢介导的生理和病理状态变化。
Biochem/physiol Actions
L-同型半胱氨酸（L-HCA）是NMDA（N-甲基-D-天冬氨酸）受体的一种内源性神经递质配体。它是谷氨酸的一种类似物，可竞争性抑制神经元中谷氨酸-半胱氨酸（xc-）反转运蛋白的功能，引起半胱氨酸摄取量下降。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Hari H Subramanian et al.
The Journal of comparative neurology, 526(2), 229-242 (2017-09-07)
The nucleus retroambiguus (NRA) is a neuronal cell group in the medullary ventrolateral tegmentum, rostrocaudally between the obex and the first cervical spinal segment. NRA neurons are premotor interneurons with direct projections to the motoneurons of soft palate, pharynx, and
M Piraud et al.
Rapid communications in mass spectrometry : RCM, 19(22), 3287-3297 (2005-10-20)
Seventy-six compounds of biological interest for the diagnosis of inherited disorders of amino acids (AA) metabolism have previously been demonstrated to be detectable in positive mode electrospray ionisation tandem mass spectrometry (ESI-MS/MS), after separation by ion-pairing reversed-phase liquid chromatography (RPLC).
Danté T Johnson et al.
The Journal of biological chemistry, 294(32), 11969-11979 (2019-07-03)
Fast photochemical oxidation of proteins (FPOP) is a MS-based method that has proved useful in studies of protein structures, interactions, conformations, and protein folding. The success of this method relies on the irreversible labeling of solvent-exposed amino acid side chains
J W Olney et al.
Brain research bulletin, 19(5), 597-602 (1987-11-01)
L-Homocysteic acid (L-HCA) has been proposed as a natural transmitter at the N-methyl-D-aspartate (NMDA) subtype of excitatory amino acid receptor based on recent evidence that L-HCA occurs L-HCA occurs naturally in the mammalian CNS, is released from K+ stimulated brain
T Knöpfel et al.
Neuroscience letters, 81(1-2), 188-192 (1987-10-16)
The effects of ionophoretically applied L-homocysteate (L-HCA), L-glutamate (L-Glu) and N-methyl-D-aspartate (NMDA) were compared in rat neocortical neurons recorded intracellularly in vitro. The firing pattern and the time course of membrane depolarization induced by L-HCA resembled those of NMDA responses.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持