生物来源
bovine brain
方案
>95% (SDS-PAGE)
表单
lyophilized powder
组成
Protein, ~10% Lowry
技术
western blot: suitable
储存温度
−20°C
基因信息
bovine ... HSPA1A(282254), HSPA8(281831)
应用
Heat shock protein 70 (Hsp70) from bovine brain has been used as a protein standard in Western blotting to check levels of the Hsp70 family proteins in honey bees after heat exposure. It has been used as a standard for the quantification of HSP70, obtained from liver sections of rats, by ELISA (enzme-linked immunosorbent assay).
生化/生理作用
HSPs (heat shock proteins) are needed for protein folding, protein assembly, protein aggregation and protein transport. They help in maintaining cellular homeostasis and offer cytoprotective effects. Hsp70 is associated with the protective effects on rat myocardial cells in presence of heat stress. Similarly, it offers neuro-protection from oxygen-glucose deprivation injury.
外形
Contains Tris buffer salts.
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
Hongbo Chen et al.
Molecular medicine reports, 11(3), 2276-2284 (2014-11-21)
The aim of the present study was to investigate the association between heat shock protein (Hsp) 70 expression kinetics and heat stress‑induced damage to rat myocardial cells in vitro and in vivo. The results showed that the activity of heart
Takehiro Sakai et al.
Transplant international : official journal of the European Society for Organ Transplantation, 16(2), 88-99 (2003-02-22)
We focused on heat shock protein 70 (HSP70) as a marker of viability in hepatic warm ischemia-reperfusion. Segmental hepatic warm ischemia was produced in rats for 15, 30, 60, 90, 120, or 180 min. Liver sections were evaluated at 30
Michelle M Elekonich
Cell stress & chaperones, 14(2), 219-226 (2008-08-13)
Foraging honey bees frequently leave the hive to gather pollen and nectar for the colony. This period of their lives is marked by periodic extremes of body temperature, metabolic expenditure, and flight muscle activity. Following ecologically relevant episodes of hyperthermia
Jian-hua Zhao et al.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 34(1), 18-22 (2014-02-06)
In the present study, we examined the effect of oxygen glucose deprivation (OGD) post-conditioning (PostC) on neural cell apoptosis in OGD-PostC model and the protective effect on primary cortical neurons against OGD injury in vitro. Four-h OGD was induced by
Leon F A van Dullemen et al.
Journal of translational medicine, 11, 22-22 (2013-01-30)
Kidneys derived from brain dead donors have lower graft survival and higher graft-function loss compared to their living donor counterpart. Heat Shock Proteins (HSP) are a large family of stress proteins involved in maintaining cell homeostasis. We studied the role
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