biological source
bovine brain
assay
>95% (SDS-PAGE)
form
lyophilized powder
composition
Protein, ~10% Lowry
technique(s)
western blot: suitable
storage temp.
−20°C
Gene Information
bovine ... HSPA1A(282254), HSPA8(281831)
Application
Heat shock protein 70 (Hsp70) from bovine brain has been used as a protein standard in Western blotting to check levels of the Hsp70 family proteins in honey bees after heat exposure. It has been used as a standard for the quantification of HSP70, obtained from liver sections of rats, by ELISA (enzme-linked immunosorbent assay).
Biochem/physiol Actions
HSPs (heat shock proteins) are needed for protein folding, protein assembly, protein aggregation and protein transport. They help in maintaining cellular homeostasis and offer cytoprotective effects. Hsp70 is associated with the protective effects on rat myocardial cells in presence of heat stress. Similarly, it offers neuro-protection from oxygen-glucose deprivation injury.
Physical form
Contains Tris buffer salts.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable