I3125
吲哚-3-丙酸
crystalline
别名:
3-（3-吲哚基）丙酸, IPA, NSC 3252, NSC 47831
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关于此项目
经验公式（希尔记法）:
C11H11NO2
化学文摘社编号:
分子量:
189.21
EC Number:
212-600-1
UNSPSC Code:
12352100
MDL number:
Beilstein/REAXYS Number:
147733
InChI
1S/C11H11NO2/c13-11(14)6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6H2,(H,13,14)
InChI key
GOLXRNDWAUTYKT-UHFFFAOYSA-N
SMILES string
OC(=O)CCc1c[nH]c2ccccc12
form
crystalline
color
light yellow
storage temp.
−20°C
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Biochem/physiol Actions
被研究作为改善肝移植后灌注的辅助手段。
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
K L Borden et al.
European journal of biochemistry, 202(2), 459-470 (1991-12-05)
The antirepressor indole 3-propanoate has been shown by X-ray crystallography to bind in a different orientation compared with the natural corepressor for the tryp repressor, L-tryptophan (Lawson, C.L. & Sigler, P. B. (1988) Nature 333, 869-871). This suggests a simple
Indole-3-propionic acid attenuates neuronal damage and oxidative stress in the ischemic hippocampus.
In Koo Hwang et al.
Journal of neuroscience research, 87(9), 2126-2137 (2009-02-25)
Tryptophan-derived indole compounds have been widely investigated as antioxidants and as free-radical scavengers. Indole-3-propionic acid (IPA), one of these compounds, is a deamination product of tryptophan. In the present study, we used Mongolian gerbils to investigate IPA's neuroprotective effects against
Burkhard Poeggeler et al.
PloS one, 5(4), e10206-e10206 (2010-04-28)
Aging is a multi-factorial process, however, it is generally accepted that reactive oxygen species (ROS) are significant contributors. Mitochondria are important players in the aging process because they produce most of the cellular ROS. Despite the strength of the free-radical
Andrew W Woodward et al.
Plant physiology, 144(2), 976-987 (2007-04-24)
The ubiquitin-like protein RELATED TO UBIQUITIN (RUB) is conjugated to CULLIN (CUL) proteins to modulate the activity of Skp1-Cullin-F-box (SCF) ubiquitylation complexes. RUB conjugation to specific target proteins is necessary for the development of many organisms, including Arabidopsis (Arabidopsis thaliana).
M Karbownik et al.
Journal of cellular biochemistry, 81(3), 507-513 (2001-03-20)
Excessive free iron and the associated oxidative damage are commonly related to carcinogenesis. Among the antioxidants known to protect against iron-induced oxidative abuse and carcinogenesis, melatonin and other indole compounds recently have received considerable attention. Indole-3-propionic acid (IPA), a deamination
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