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Merck
CN
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About This Item

MDL编号:
UNSPSC代码:
12352202
NACRES:
NA.32
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生物来源

human

质量水平

重组

expressed in E. coli

方案

≥98% (SDS-PAGE)

表单

lyophilized powder

分子量

~17 kDa

包装

pkg of 0.1 mg

技术

cell culture | mammalian: suitable

杂质

≤1 EU/μg endotoxin

颜色

white

溶解性

water: soluble 1.000 mL, clear, colorless

UniProt登记号

储存温度

−20°C

基因信息

human ... IFNG(3458)

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应用

Interferon-γ human has been used:
  • to study the effect of interferon-γ on cultured trophoblasts in absence and presence of fibronectin
  • to analyse factors which participate in the production of antibody microarrays on glass support
  • for ELISA (enzyme-linked immunosorbent assay) method to understand the effect of interferon-γ in human gingival fibroblasts in presence of bacterial challenge

生化/生理作用

IFNG (interferon-γ) is a type-2 interferon which is produced by Th (T helper cells)-1 lymphocytes, CD8 cytotoxic lymphocytes, natural killer (NK) cells, and natural killer T (NKT) cells. It plays an important role in innate and adaptive immune responses, and helps in defense against bacterial infections, dimorphic yeast and some viral infections. High expression of IFNG is common in many autoimmune diseases, such as systemic lupus erythematosis, Sjögren syndrome, inflammatory bowel disease and multiple sclerosis.

外形

Lyophilized from phosphate buffered saline.

分析说明

The biological activity is measured by a viral resistance assay.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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