I4659
ICRF-193
synthetic (organic), ≥95%, topoisomerase II inhibitor, solid,powder or flakes
别名:
meso-4,4′-(3,2-丁二基)-双(2,6-哌嗪二酮)
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关于此项目
经验公式（希尔记法）:
C12H18N4O4
化学文摘社编号:
分子量:
282.30
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥95%
Form:
powder or flakes, solid
产品名称
ICRF-193, apoptosis inducer, arabinosidase substrate
biological source
synthetic (organic)
Quality Segment
assay
≥95%
form
powder or flakes, solid
solubility
DMSO: 4 mg/mL
storage temp.
−20°C
SMILES string
C[C@@H]([C@@H](C)N1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2
InChI
1S/C12H18N4O4/c1-7(15-3-9(17)13-10(18)4-15)8(2)16-5-11(19)14-12(20)6-16/h7-8H,3-6H2,1-2H3,(H,13,17,18)(H,14,19,20)/t7-,8+
InChI key
OBYGAPWKTPDTAS-OCAPTIKFSA-N
General description
ICRF-193是一种双二哌嗪衍生物。它通过形成不可裂解的复合物来抑制拓扑异构酶II。
Application
ICRF-193已被用作拓扑异构酶II（TOP2）抑制剂，用于处理小鼠卵母细胞，以研究TOP2在减数分裂中的作用。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Skin Sens. 1
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves