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Merck
CN

J2000

Sigma-Aldrich

保幼激素III

≥65%, liquid, non-sterile

别名:

甲基法尼酯,10,11-环氧化物, C16-保幼激素, JH-III, 反,反-10,11-环氧-3,7,11-三甲基-2,6-十二碳二烯酸甲酯, 烟草天蛾激素

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关于此项目

经验公式(希尔记法):
C16H26O3
化学文摘社编号:
分子量:
266.38
Beilstein:
1316317
EC 号:
MDL编号:
UNSPSC代码:
51111800
PubChem化学物质编号:
NACRES:
NA.32
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生物来源

synthetic (organic)

质量水平

无菌性

non-sterile

方案

≥65% (HPLC)

表单

liquid

浓度

≥65%

技术

activity assay: suitable

运输

ambient

储存温度

−20°C

SMILES字符串

COC(=O)\C=C(/C)CC\C=C(/C)CC[C@H]1OC1(C)C

InChI

1S/C16H26O3/c1-12(9-10-14-16(3,4)19-14)7-6-8-13(2)11-15(17)18-5/h7,11,14H,6,8-10H2,1-5H3/b12-7+,13-11+

InChI key

QVJMXSGZTCGLHZ-ZPLWXOMKSA-N

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一般描述

研究领域:细胞信号传导

保幼激素III (JH III)是昆虫体内最普遍的保幼激素 (JH)。

应用

保幼激素 III 已用于:
  • 保幼激素对褶皱臂尾轮虫混交雌体的产生的影响
  • 研究保幼激素对成年蜜蜂头部 GB19811(假定的Takeout/保幼激素结合蛋白)mRNA 水平的影响
  • 研究保幼激素对地熊蜂促促性腺和生理功能的影响

生化/生理作用

JHBP(JH 结合蛋白)可保护JH(保幼激素)免受JH酯酶和环氧化物水解酶介导降解。它们还有助于将JH传递到靶组织。保幼激素(JHs) 是一组无环倍半萜类化合物,在某些昆虫谱系中,这些化合物的法尼醇骨架经过化学修饰,产生一系列同源激素。JH是昆虫发育和繁殖全方位必需的成分。它在社会性昆虫的变态和等级决定中具有关键作用。它可调节行为、多形性、幼虫和成虫滞育以及卵巢发育。保幼激素 III (JH III) 的倍半萜类骨架是通过蟑螂的经典甲羟戊酸(MVA)途径生物合成的。
控制昆虫的幼虫变态,包括保留幼体特征。

危险声明

危险分类

Aquatic Chronic 4

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

涉药品监管产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Toyomi Kotaki et al.
Journal of insect physiology, 57(1), 147-152 (2010-10-26)
Juvenile hormone III skipped bisepoxide (JHSB(3)), methyl (2R,3S,10R)-2,3;10,11-bisepoxyfarnesoate was recently determined as a novel juvenile hormone (JH) in a stink bug, Plautia stali. To further confirm the biological function of JHSB(3) in this insect, its juvenilizing, reproduction-stimulating and diapause-terminating activities
Linquan Ge et al.
Frontiers in physiology, 11, 579233-579233 (2020-10-13)
The mirid bug, Cyrtorhinus lividipennis Reuter, is an important predator of rice planthoppers in Asia. In a previous study, C. lividipennis fed on gramineous weeds with brown planthopper (BPH) eggs had reduced development compared to those fed on rice with
Tzachi Hagai et al.
Insect biochemistry and molecular biology, 37(7), 689-701 (2007-06-07)
We identified and characterized eight genes encoding putative Takeout/juvenile hormone binding proteins (To/JHBP) in the honeybee genome. Phylogenetic analyses revealed nine distinct lineages within this gene family, including those containing Takeout (To) and JHBP for which there are no honeybee
Shuang Guo et al.
PLoS genetics, 17(2), e1009352-e1009352 (2021-02-03)
Diapause, a programmed developmental arrest primarily induced by seasonal environmental changes, is very common in the animal kingdom, and found in vertebrates and invertebrates alike. Diapause provides an adaptive advantage to animals, as it increases the odds of surviving adverse
A Ishikawa et al.
Insect molecular biology, 21(1), 49-60 (2011-10-13)
Most aphids show reproductive polyphenism, i.e. they alternate their reproductive modes from parthenogenesis to sexual reproduction in response to short photoperiods. Although juvenile hormone (JH) has been considered a likely candidate for regulating the transition from asexual to sexual reproduction

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