J2000
保幼激素III
≥65%, liquid, non-sterile
别名:
甲基法尼酯，10,11-环氧化物, C16-保幼激素, JH-III, 反,反-10,11-环氧-3,7,11-三甲基-2,6-十二碳二烯酸甲酯, 烟草天蛾激素
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关于此项目
经验公式（希尔记法）:
C16H26O3
化学文摘社编号:
分子量:
266.38
UNSPSC Code:
51111800
NACRES:
NA.32
PubChem Substance ID:
EC Number:
246-072-9
Beilstein/REAXYS Number:
1316317
MDL number:
Biological source:
synthetic (organic)
Form:
liquid
Assay:
≥65% (HPLC)
产品名称
保幼激素III, ≥65%, liquid, non-sterile
InChI key
QVJMXSGZTCGLHZ-ZPLWXOMKSA-N
InChI
1S/C16H26O3/c1-12(9-10-14-16(3,4)19-14)7-6-8-13(2)11-15(17)18-5/h7,11,14H,6,8-10H2,1-5H3/b12-7+,13-11+
SMILES string
COC(=O)\C=C(/C)CC\C=C(/C)CC[C@H]1OC1(C)C
biological source
synthetic (organic)
sterility
non-sterile
assay
≥65% (HPLC)
form
liquid
concentration
≥65%
technique(s)
activity assay: suitable
shipped in
ambient
storage temp.
−20°C
Quality Level
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Application
保幼激素 III 已用于：
- 保幼激素对褶皱臂尾轮虫混交雌体的产生的影响
- 研究保幼激素对成年蜜蜂头部 GB19811（假定的Takeout/保幼激素结合蛋白）mRNA 水平的影响
- 研究保幼激素对地熊蜂促促性腺和生理功能的影响
Biochem/physiol Actions
JHBP（JH 结合蛋白）可保护JH（保幼激素）免受JH酯酶和环氧化物水解酶介导降解。它们还有助于将JH传递到靶组织。保幼激素(JHs) 是一组无环倍半萜类化合物，在某些昆虫谱系中，这些化合物的法尼醇骨架经过化学修饰，产生一系列同源激素。JH是昆虫发育和繁殖全方位必需的成分。它在社会性昆虫的变态和等级决定中具有关键作用。它可调节行为、多形性、幼虫和成虫滞育以及卵巢发育。保幼激素 III (JH III) 的倍半萜类骨架是通过蟑螂的经典甲羟戊酸(MVA)途径生物合成的。
控制昆虫的幼虫变态，包括保留幼体特征。
General description
研究领域：细胞信号传导
保幼激素III (JH III)是昆虫体内最普遍的保幼激素 (JH)。
保幼激素III (JH III)是昆虫体内最普遍的保幼激素 (JH)。
hcodes
Hazard Classifications
Aquatic Chronic 4
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
涉药品监管产品
此项目有
Michael E Scharf et al.
Insect biochemistry and molecular biology, 35(3), 207-215 (2005-02-12)
Termites express polyphenism during caste differentiation that is mostly undefined at the molecular level. Using the eastern subterranean termite, Reticulitermes flavipes Kollar, we wanted (1) to test juvenile hormone (JH) model assays for their ability to induce detectable molecular changes
Jesus Lozano et al.
Scientific reports, 1, 163-163 (2012-02-23)
Insect metamorphosis is regulated by ecdysteroids, which induce molts, and juvenile hormone (JH), which inhibits metamorphic changes. The molecular action of ecdysteroids has been thoroughly studied, but that of JH is poorly understood, with data currently only being available for
A Ishikawa et al.
Insect molecular biology, 21(1), 49-60 (2011-10-13)
Most aphids show reproductive polyphenism, i.e. they alternate their reproductive modes from parthenogenesis to sexual reproduction in response to short photoperiods. Although juvenile hormone (JH) has been considered a likely candidate for regulating the transition from asexual to sexual reproduction
Cheolho Sim et al.
Insect molecular biology, 22(1), 1-11 (2012-11-06)
Juvenile hormone (JH) controls diverse physiological and developmental events including diapause and nutrient metabolism. The focal point of endocrine regulation in adult reproductive diapause is initiated by a halt of JH synthesis. In diapausing females of the mosquito Culex pipiens
Shuang Guo et al.
PLoS genetics, 17(2), e1009352-e1009352 (2021-02-03)
Diapause, a programmed developmental arrest primarily induced by seasonal environmental changes, is very common in the animal kingdom, and found in vertebrates and invertebrates alike. Diapause provides an adaptive advantage to animals, as it increases the odds of surviving adverse
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