生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
种属反应性
mouse, human
技术
western blot: 0.5 μg/mL using mouse neuronal cell extract
UniProt登记号
运输
dry ice
储存温度
−20°C
基因信息
human ... KIF5B(3799)
mouse ... Kif5b(16573)
一般描述
The gene KIF5B (kinesin 5B) is mapped to human chromosome 10p11.22. It encodes a conventional kinesin that contains two heavy chains and two light chains forming a heterotetramer. It is abundantly expressed in adipocytes.
免疫原
synthetic peptide corresponding to amino acid residues 376-396 from human kinesin 5B.
应用
Anti-Kinesin 5B antibody produced in rabbit has been used in immunoprecipitation.
生化/生理作用
The gene KIF5B (kinesin 5B) encodes a kinesin that is involved in the transportation of GLUT4 (glucose transporter protein) to the plasma membrane in response to insulin, thereby regulating insulin signaling pathway. It participates in the translocation of certain apical proteins to the apical membrane.
外形
Solution in phosphate buffered saline containing 1 mg/mL BSA and 0.05% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
Conventional kinesin KIF5B mediates insulin-stimulated GLUT4 movements on microtubules.
Semiz S
The Embo Journal, 22, 2387-2399 (2003)
A transforming KIF5B and RET gene fusion in lung adenocarcinoma revealed from whole-genome and transcriptome sequencing.
Ju YS
Genome Research, 22, 436-445 (2012)
Polarization-dependent selective transport to the apical membrane by KIF5B in MDCK cells.
Jaulin F
Developmental Cell, 13, 511-522 (2007)
Raed Hanania et al.
The Journal of biological chemistry, 287(11), 8468-8483 (2012-01-25)
As major effector cells of the innate immune response, macrophages must adeptly migrate from blood to infected tissues. Endothelial transmigration is accomplished by matrix metalloproteinase (MMP)-induced degradation of basement membrane and extracellular matrix components. The classical activation of macrophages with
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