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Merck
CN

K2126

Sigma-Aldrich

β-Estradiol-6-one 6-(O-carboxymethyloxime)

≥98.00% (TLC), powder

别名:

β-Estradiol-6-(O-carboxymethyl)oxime, 1,3,5(10)-Estratriene-3,17β-diol-6-one6-(O-carboxymethyloxime), 3,17β-Dihydroxy-1,3,5(10)-estratriene 6-(O-carboxymethyl)oxime, 6-Ketoestradiol 6-(O-carboxymethyloxime)

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关于此项目

经验公式（希尔记法）:
C20H25NO5
化学文摘社编号:
35048-47-6
分子量:
359.42
Beilstein:
2484202
MDL编号:
MFCD00056459
UNSPSC代码:
51111800
PubChem化学物质编号:
329817132
NACRES:
NA.77

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产品名称

β-Estradiol-6-one 6-(O-carboxymethyloxime),

生物来源

synthetic (organic)

质量水平

200

方案

≥98.00% (TLC)

表单

powder

溶解性

ethanol: 19.60-20.40 mg/mL, clear, colorless to faintly yellow

运输

ambient

储存温度

2-8°C

SMILES字符串

C[C@]12CC[C@H]3[C@@H](C\C(=N\OCC(O)=O)c4cc(O)ccc34)[C@@H]1CC[C@@H]2O

InChI

1S/C20H25NO5/c1-20-7-6-13-12-3-2-11(22)8-15(12)17(21-26-10-19(24)25)9-14(13)16(20)4-5-18(20)23/h2-3,8,13-14,16,18,22-23H,4-7,9-10H2,1H3,(H,24,25)/b21-17-/t13-,14-,16+,18+,20+/m1/s1

InChI key

AWARIMYXKAIIGO-UYGYUSPXSA-N

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相关类别

一般描述

β-Estradiol-6-one 6-(O-carboxymethyloxime) is a derivative of 17β-estradiol.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000427378
0000427378
0000388379
0000365346
0000365345

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C J Meijer et al.
Virchows Archiv. B, Cell pathology including molecular pathology, 40(1), 27-37 (1982-01-01)
The present study defines criteria for determining the presence of estrogen-receptors in human breast carcinomas demonstrated by a histochemical assay using 17 beta-estradiol-carboxy-methyl-oxim-bovine serum albumen-FITC. The criteria were: 1) the percentage of cells showing fluorescence; 2) the intensity of the
M Malawer et al.
Journal of surgical oncology, 25(3), 148-152 (1984-03-01)
Hormonal receptors of giant cell tumors (GCTs) have not been previously reported. Five cases of GCT of bone were analyzed for estrogen and progesterone binding. Frozen sections were studied by a histochemical method, using 17-beta-6-CMOBSA-FITC and 11-alpha-hydroxyprogesterone-HS-BSA-TMRITC. Cytoplasmic fluorescence with
Markus Lacorn et al.
Journal of immunological methods, 297(1-2), 225-236 (2005-03-22)
17beta-estradiol (E2) concentrations are in the low pg/ml range in plasma. To develop a sensitive enzyme immunoassay (EIA) for E2-determination a highly specific antibody raised against a 6-carboxymethyl (CMO)-E2-bovine serum albumine conjugate was used. Based on 6-CMO-E2 and 6-amino-E2, four
Histochemical estrogen receptor assay.
S H Lee
American journal of clinical pathology, 76(3), 365-365 (1981-09-01)
K S McCarty et al.
Cancer, 46(12 Suppl), 2842-2845 (1980-12-15)
Three histochemical techniques for estrogen binding localization in tissue sections were compared to sucrose density gradient analyses for estrogen receptor in 186 breast carcinomas. Apparent localization to epithelial elements was noted using 6-BSA-Fluor-CMO-17 beta-estradiol, 17-BSA-Fluor-TSC-estrogen, and polyestradiol phosphate/anti-estradiol antibody methods.
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