InChI key
HSMPDPBYAYSOBC-UHFFFAOYSA-N
InChI
1S/C14H12O5/c1-7-6-9(15)10-11(16-2)8-4-5-18-12(8)14(17-3)13(10)19-7/h4-6H,1-3H3
SMILES string
COc1c2OC(C)=CC(=O)c2c(OC)c3ccoc13
form
crystalline
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
color
light yellow
bp
180-200 °C/0.05 mmHg (lit.)
mp
150-154 °C (lit.)
format
neat
storage temp.
−20°C
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General description
Khellin is a drug, which belongs to the group of furochromones.It is isolated from a perennial plant named Ammivisnaga L, that usually grows in the mediterranean regions.
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
新产品
此项目有
Total synthesis of khellin via a chromium carbene complex
Yamashita A
Journal of the American Chemical Society, 107(20), 5823-5824 (1985)
Fatma A Ragab et al.
European journal of medicinal chemistry, 42(8), 1117-1127 (2007-03-10)
The synthesis of 9- and 6-alkylaminomethyl furoflavones 5a, b, 9a-c, 13a, b, 15a-g and 18 from the naturally occurring chromones visnagin and khellin. Gastroprotective potency of these compounds in the ethanol damage model was determined. The results indicate that, through
Karin G Haug et al.
Planta medica, 78(17), 1831-1836 (2012-10-26)
The furanochromone visnagin is one of the main compounds of Ammi visnaga L. (syn. Khella) with potential effects on kidney stone prevention. After determination of the pharmacokinetic properties of visnagin after intravenous bolus administration in rats, the aim of the
Pattaraporn Vanachayangkul et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 877(7), 653-656 (2009-02-04)
A rapid and sensitive method for the determination of visnagin in rat plasma was developed using liquid chromatography tandem mass spectrometry (LC-MS/MS). The plasma samples were processed by protein precipitation with methanol:acetonitrile (25:75) and warfarin was used as the internal
J de Leeuw et al.
Journal of the European Academy of Dermatology and Venereology : JEADV, 25(1), 74-81 (2010-05-19)
Various surgical and non-surgical methods are available to treat vitiligo. Surgical techniques such as epidermal blister graft transplantation may be effective for the re-pigmentation of stable, but refractory vitiligo areas. Khellin has phototherapeutic properties that are similar to those of
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