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Merck
CN

K2769

Sigma-Aldrich

Monoclonal Anti-Keap1 antibody produced in mouse

~1.0 mg/mL, clone Keap1-2, purified immunoglobulin, buffered aqueous solution

别名:

Anti-Cytosolic inhibitor of Nrf2, Anti-INrf2, Anti-Kelch-like ECH-associated protein 1

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UNSPSC代码:
12352203
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生物来源

mouse

偶联物

unconjugated

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

Keap1-2, monoclonal

表单

buffered aqueous solution

分子量

antigen ~69 kDa

种属反应性

human

浓度

~1.0 mg/mL

技术

western blot: 2-4 μg/mL using whole extract of human Jurkat cells

同位素/亚型

IgG1

UniProt登记号

运输

dry ice

储存温度

−20°C

基因信息

human ... KEAP1(9817)

外形

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

12 - Non Combustible Liquids

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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M Hussong et al.
Cell death & disease, 5, e1195-e1195 (2014-04-26)
The epigenetic sensor BRD4 (bromodomain protein 4) is a potent target for anti-cancer therapies. To study the transcriptional impact of BRD4 in cancer, we generated an expression signature of BRD4 knockdown cells and found oxidative stress response genes significantly enriched.
Jennifer Yinuo Cao et al.
Cell reports, 26(6), 1544-1556 (2019-02-07)
The tripeptide glutathione suppresses the iron-dependent, non-apoptotic cell death process of ferroptosis. How glutathione abundance is regulated in the cell and how this regulation alters ferroptosis sensitivity is poorly understood. Using genome-wide human haploid genetic screening technology coupled to fluorescence-activated
Jianglin Ma et al.
Molecular and cellular biology, 32(8), 1506-1517 (2012-02-15)
PALB2/FANCN is mutated in breast and pancreatic cancers and Fanconi anemia (FA). It controls the intranuclear localization, stability, and DNA repair function of BRCA2 and links BRCA1 and BRCA2 in DNA homologous recombination repair and breast cancer suppression. Here, we
Jiexiong Yao et al.
Inflammation, 42(2), 471-484 (2019-02-09)
Paraquat (PQ) intoxication seriously endangers human beings' health, however, the underlying mechanisms are still unclear. Here we found that PQ inhibits human bronchial 16HBE cell proliferation and promotes cell apoptosis, necrosis as well as ROS generation in a dose dependent

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