form
lyophilized powder
Quality Level
potency
<0.1 μg per mL agglutination activity
quality
Affinity-purified
impurities
salt, free
storage temp.
−20°C
General description
从 Arachis hypogaea (花生)中提取的凝集素是分子量 110 kDa的同四聚体蛋白。
Application
从 Arachis hypogaea (花生)中提取的凝集素用于:
- 检测 Thomson-Friedenreich 抗原
- 作为PBS的成分,研究其对细胞活力的影响
- 研究其阻断结合位点的能力
Biochem/physiol Actions
从Arachis hypogaea (花生)中提取的凝集素对 Thomson − Friedenreich 抗原的 β -D-Gal(1-3)-D-galNAc 残基具有特异性。 在许多鳞状细胞癌诊断和预后中,是最广泛使用的标志物。
花生凝集素不会凝集正常的人类红细胞,但会强烈凝集神经氨酸酶处理的红细胞。花生凝集素具有与人血清中的抗 T 抗体相似的有效抗 T 活性。凝集素可用于区分人淋巴细胞亚群。
Analysis Note
凝集活性以 μg/ml 表示,并根据 1 mg/mL 溶液在磷酸盐缓冲盐水 (pH 6.8) 中的系列稀释液测定。该活性是在 25°C 下孵育 1 h 后凝集 2% 神经氨酸酶处理的人 O 型红细胞悬液的最低浓度。
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
低风险生物材料
此项目有
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全球贸易项目编号
| 货号 | GTIN |
|---|---|
| L0881-10MG | 04061833263006 |
| L0881-5MG | 04061833949061 |
| L0881-25MG | 04061833949054 |