L135
L-741,626
≥98% (HPLC)
别名:
(±)-3-[4-(4-Chlorophenyl)-4-hydroxypiperidinyl]methylindole
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关于此项目
经验公式（希尔记法）:
C20H21ClN2O
化学文摘社编号:
分子量:
340.85
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: ≥20 mg/mL, ethanol: 24 mg/mL, H2O: insoluble
storage temp.
room temp
SMILES string
OC1(CCN(CC1)Cc2c[nH]c3ccccc23)c4ccc(Cl)cc4
InChI
1S/C20H21ClN2O/c21-17-7-5-16(6-8-17)20(24)9-11-23(12-10-20)14-15-13-22-19-4-2-1-3-18(15)19/h1-8,13,22,24H,9-12,14H2
InChI key
LLBLNMUONVVVPG-UHFFFAOYSA-N
Gene Information
human ... DRD2(1813), DRD3(1814), DRD4(1815)
Application
L-741,626 has been used as selective dopamine (D2) receptor antagonist to study its effects on the uptake of dopamine in human embryonic kidney 293 (HEK293) cells. It has also been used as a D2 receptor antagonist to study its effects on thyrotropin-releasing hormone (TRH) induced prolactin release.
Biochem/physiol Actions
L-741,626 is a selective dopamine (D2) receptor antagonist.
Features and Benefits
This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)