Merck
CN
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文件

L135

Sigma-Aldrich

L-741,626

≥98% (HPLC)

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别名:
(±)-3-[4-(4-Chlorophenyl)-4-hydroxypiperidinyl]methylindole
经验公式（希尔记法）:
C20H21ClN2O
CAS号:
81226-60-0
分子量:
340.85
MDL编号:
MFCD00953632
PubChem化学物质编号:
24278529
NACRES:
NA.77

质量水平

100

检测方案

≥98% (HPLC)

形式

powder

颜色

white to beige

溶解性

DMSO: ≥20 mg/mL
ethanol: 24 mg/mL
H2O: insoluble

储存温度

room temp

SMILES字符串

OC1(CCN(CC1)Cc2c[nH]c3ccccc23)c4ccc(Cl)cc4

InChI

1S/C20H21ClN2O/c21-17-7-5-16(6-8-17)20(24)9-11-23(12-10-20)14-15-13-22-19-4-2-1-3-18(15)19/h1-8,13,22,24H,9-12,14H2

InChI key

LLBLNMUONVVVPG-UHFFFAOYSA-N

基因信息

human ... DRD2(1813) , DRD3(1814) , DRD4(1815)

应用

L-741,626 has been used as selective dopamine (D2) receptor antagonist to study its effects on the uptake of dopamine in human embryonic kidney 293 (HEK293) cells. It has also been used as a D2 receptor antagonist to study its effects on thyrotropin-releasing hormone (TRH) induced prolactin release.

生化/生理作用

L-741,626 is a selective dopamine (D2) receptor antagonist.

特点和优势

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

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