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Merck
CN

L4879

Lumiflavine

powder

别名:

7,8,10-Trimethylbenzo[g]pteridine-2,4(3H,10H)-dione, 7,8,10-Trimethylisoalloxazine

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经验公式(希尔记法):
C13H12N4O2
化学文摘社编号:
分子量:
256.26
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
214-125-5
MDL number:
Beilstein/REAXYS Number:
269756
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SMILES string

CN1c2cc(C)c(C)cc2N=C3C(=O)NC(=O)N=C13

form

powder

storage temp.

−20°C

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Biochem/physiol Actions

Lumiflavine (Lumiflavin) is produced by the photolysis of vitamin B2 (Riboflavin). Lumiflavine, a riboflavin uptake inhibitor, is used to study riboflavin uptake in intestinal epithelial (Caco-2) and other epithelial cells.

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Health hazard

signalword

Warning

hcodes

Hazard Classifications

Muta. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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分析证书(COA)

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Minako Kondo et al.
The journal of physical chemistry. B, 110(41), 20107-20110 (2006-10-13)
Ultrafast time-resolved infrared (TRIR) spectra of flavin adenine dinucleotide (FAD) and the anion of lumiflavin (Lf-) are described. Ground-state recovery and excited-state decay of FAD reveal a common dominant ultrafast relaxation and a minor slower component. The Lf- transient lacks
Atsuko Satoh et al.
Journal of biochemistry, 134(2), 297-304 (2003-09-11)
The flavoenzyme medium-chain acyl-CoA dehydrogenase (MCAD) eliminates the alpha-proton of the substrate analog, 3-thiaoctanoyl-CoA (3S-C8-CoA), to form a charge-transfer complex with deprotonated 3S-C8-CoA. This complex can simulate the metastable reaction intermediate immediately after the alpha-proton elimination of a substrate and
Maxime T A Alexandre et al.
Biophysical journal, 97(1), 227-237 (2009-07-08)
Phototropins, major blue-light receptors in plants, are sensitive to blue light through a pair of flavin mononucleotide (FMN)-binding light oxygen and voltage (LOV) domains, LOV1 and LOV2. LOV2 undergoes a photocycle involving light-driven covalent adduct formation between a conserved cysteine
H M Said et al.
The American journal of physiology, 266(1 Pt 1), G15-G21 (1994-01-01)
The cellular and molecular regulation of intestinal absorption of the water-soluble vitamin riboflavine (RF) is poorly understood. The availability of a suitable in vitro cultured system that possesses the transport characteristics of the native intestinal absorptive cells would provide a
Yasuyuki Yamada et al.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 11(8), 1007-1023 (2006-09-01)
DNA photolyases (EC 4.1.99.3) are enzymes that catalyze photoreversion of cis,syn-thymine photodimer (T[c,s]T), which is one of major photolesion products in DNA, by utilizing UV light. In this work, we have designed and synthesized Zn2+ -1,4,7,10-tetraazacyclododecane complexes bearing a lumiflavin

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