L7395
脂肪氧化酶 来源于大豆
Type I-B, lyophilized powder, ≥50,000 units/mg solid
别名:
15-脂氧合酶, LOX A, 亚油酸：氧氧化还原酶, 脂氧合酶
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关于此项目
化学文摘社编号:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-853-1
MDL number:
EC 号:
Specific activity:
≥50,000 units/mg solid
Application
大豆酶将使用花生四烯酸作为底物，以亚油酸作为底物的活性约为 15%；花生四烯酸氧化的产物是 12-或 15-过氧化氢花生四烯酸（12-HPETE 或 15-HPETE）。
来自大豆的脂氧合酶已用于：
- 研究2-(α-D-吡喃葡萄糖基)甲基-2,5,7,8-四甲基色胺-6-醇(TMG)对脂蛋白氧化的影响
- 作为脂氧合酶的代表酶，在微孔板检测平台上筛选木材提取物降解酶
- 作为脂氧合酶抑制活性检测的阳性对照品
Biochem/physiol Actions
催化含有顺式，顺式-1,4-戊二烯结构的脂质的氢过氧化。
在接近100℃的温度下热处理5到10分钟，使脂氧合酶失活。研究表明，γ辐射处理降低了大豆脂氧合酶的比活性。这类酶可用于与哮喘和过敏相关的研究。脂氧合酶适用于工业生物转化，如芳香精细化学品的生产。
General description
脂氧化酶(LOX)又名脂氧合酶，是一种非血红素铁蛋白。脂氧合酶在植物、部分微生物和动物中广泛存在。根据pH值和最适温度、底物特异性以及不同试剂的抑制程度，分为LOX-1、LOX-2和LOX-3。
Other Notes
当亚油酸为 3.0 mL 体积（1 cm 光径）底物时，25°C、pH 9.0 条件下 1 个单位每分钟将导致 A 234 增加 0.001。一个 A 234 单位相当于氧化 0.12μ 摩尔亚油酸。
Physical form
含有稳定剂和 NaCl
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
动植物源性产品
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