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Merck
CN

M0567

来自肝脏的微粒体,合并

from human male

别名:

lab equipment accessory

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关于此项目

NACRES:
NA.54
UNSPSC Code:
12352204
Biological source:
human male
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biological source

human male

Quality Segment

form

liquid

packaging

vial of ~10 mg

shipped in

dry ice

storage temp.

−70°C

Application

Microsomes from Liver, Pooled has been used:
  • in the glucuronidation kinetics assay to test the effects of herbal extracts on glucuronidation process
  • as a human liver microsomes (HLM) matrix for testing metabolic stability of talazoparib using liquid chromatography-tandem mass spectrometry (LC–MS/MS)
  • to study the metabolization of enantiomeric peptide D3

Microsomes from liver have been used in a study to assess differences in enzymatic activities between normal rat livers and from liver after partial hepatectomy. They have also been used in a study to investigate the carbon monoxide-binding pigment in liver microsomes.

Biochem/physiol Actions

肝微粒体是来源于肝细胞内质网的亚细胞颗粒。这些微粒体是药物代谢酶(包括细胞色素 P-450)的丰富来源。不同来源的微粒体池有助于研究外源代谢和药物相互作用。
药物代谢酶的来源,包括细胞色素 P-450。
N-glucuronidation of various 1-substituted imidazoles was found to occur in human liver microsomes.


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存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品

此项目有



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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相关内容






全球贸易项目编号

货号GTIN
M0567-1VL04061833993415