Macrophage-Derived Chemokine (MDC) induces chemotaxis or calcium mobilization in dendritic cells, IL-2 activated cells, and activated T lymphocytes. MDC, also named stimulated T cell chemotactic protein (STCP-1), shows <35% identity to other CC chemokine family members. It is expressed in dendritic cells, macrophages, and activated monocytes. Expression is also detected in the tissues of thymus, lymph node, and appendix.

Lyophilized from a 0.2 μm filtered solution in 20% acetonitrile and 0.1% trifluoroacetic acid containing 1.25 mg bovine serum albumin.

The biological activity is measured by its ability to chemoattract human T-lymphoblastoid CEM-NKr cells.