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Merck
CN

M3277

Methoxypolyethylene glycol activated with cyanuric chloride

average mol wt 5,000

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线性分子式:
CH3O(CH2CH2O)n-C3N3Cl2
UNSPSC Code:
12161900
MDL number:
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mol wt

average mol wt 5,000

storage temp.

−20°C

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Application

Methoxypolyethylene glycol activated with cyanuric chloride has been used in a study to assess the biophysical consequences of linker chemistry and polymer size on stealth erythrocytes. It has also been used in a study to quantify dithiothreitol displacement of functional ligands from gold nanoparticles. This detergent is also for modification of proteins; it may improve solubility and extend biological lifetime.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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分析证书(COA)

Lot/Batch Number

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Quantifying dithiothreitol displacement of functional ligands from gold nanoparticles
Tsai, D., et al.
Analytical and Bioanalytical Chemistry, 3015-3023 (2012)
C J Jackson et al.
Analytical biochemistry, 165(1), 114-127 (1987-08-15)
The experimental conditions for the preparation of conjugates of ovalbumin (OA) and monomethoxypolyethylene glycol (mPEG) of a preselected average degree of conjugation, n, using cyanuric chloride as the coupling agent, have been investigated with emphasis on purification and characterization of
A Abuchowski et al.
The Journal of biological chemistry, 252(11), 3578-3581 (1977-06-10)
Methoxypolyethylene glycols of 1900 and 5000 daltons have been attached covalently to bovine serum albumin using cyanuric chloride as the coupling agent. When sufficient polymer is attached, the modified bovine serum albumin appears to lose its immunogenicity in the rabbit
Amanda J Bradley et al.
Biochimica et biophysica acta, 1561(2), 147-158 (2002-05-09)
Immunocamouflaged red blood cells (RBC) are produced by cell surface derivatization with methoxypolyethylene glycol (mPEG). These immunologically attenuated cells may reduce the risk of allosensitization in chronically transfused patients. To characterize the effects of differing linker chemistries and polymer lengths

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