M3547
芒果甙 芒果
别名:
1,3,6,7-四羟基氧杂蒽酮 C 2-β- D -葡萄糖苷
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关于此项目
经验公式（希尔记法）:
C19H18O11
化学文摘社编号:
分子量:
422.34
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352205
MDL number:
InChI
1S/C19H18O11/c20-4-11-15(25)17(27)18(28)19(30-11)12-8(23)3-10-13(16(12)26)14(24)5-1-6(21)7(22)2-9(5)29-10/h1-3,11,15,17-23,25-28H,4H2/t11-,15-,17+,18-,19+/m1/s1
SMILES string
OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)cc3Oc4cc(O)c(O)cc4C(=O)c3c2O
InChI key
AEDDIBAIWPIIBD-ZJKJAXBQSA-N
assay
≥98% (TLC)
form
powder
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
Quality Level
General description
芒果苷(Mangiferin, MGF)是从芒果树中分离得到的天然生物活性多酚类物质，由氧杂蒽酮葡萄糖苷构成。芒果苷也存在于其他被子植物和草本植物中。
Application
芒果苷已用于：
- 作为超声-三相分离(UTPP)法表征芒果来源芒果苷的参考标准品
- 研究其在促进棕色脂肪表型鼠C3H10T1/2间充质干细胞(MSC)方面及在线粒体生物合成和稳态中的作用
- 作为参考标准品，通过高效薄层色谱法(HPTLC)定量测定宽丝獐牙菜Swertia paniculata芽培养物中的标记化合物
Biochem/physiol Actions
芒果苷具有抗氧化、抗糖尿、抗菌、心脏保护、神经保护和免疫调节等多种药理活性。它对链脲菌素诱导的糖尿病大鼠具有抗糖尿、抗高血脂和抗动脉粥样硬化作用。芒果苷具有化疗和化学预防活性。它对四氯化碳诱导的肝损伤具有抗氧化、镇痛和肝保护作用。芒果苷是一种胃肠道传输(GIT)加速剂。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 1 Oral
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Ahsana Dar et al.
Biological & pharmaceutical bulletin, 28(4), 596-600 (2005-04-02)
Mangiferin, 2-beta-D-glucopyranosyl-1,3,6,7-tetrahydroxy-9H-xanthen-9-one, obtained directly from methanolic extracts of Bombax ceiba leaves in substantial amounts demonstrated strong antioxidant activity (EC(50) 5.8+/-0.96 mug/ml or 13.74 muM) using DPPH assay comparable to rutin, commonly used as antioxidant for medical purposes. The acetyl and
Fuchsia Gold-Smith et al.
Nutrients, 8(7) (2016-07-02)
Mangiferin, a bioactive compound derived primarily from Anacardiaceae and Gentianaceae families and found in mangoes and honeybush tea, has been extensively studied for its therapeutic properties. Mangiferin has shown promising chemotherapeutic and chemopreventative potential. This review focuses on the effect
Md Shamim Rahman et al.
Metabolism: clinical and experimental, 107, 154228-154228 (2020-04-15)
Mangiferin (MF), a xanthonoid derived from Mangifera indica, has shown therapeutic effects on various human diseases including cancer, diabetes, and obesity. Nonetheless, the influence of MF on non-shivering thermogenesis and its underlying mechanism in browning remains unclear. Here, our aim
Zhongtao Wu et al.
The Journal of organic chemistry, 75(16), 5725-5728 (2010-08-14)
Mangiferin, isomangiferin, and homomangiferin, the xanthone C-glycosides with a wide spectrum of pharmacological effects, were synthesized concisely, featuring a C-glycosylation of a xanthene derivative with perbenzylglucopyranosyl N-phenyltrifluoroacetimidate.
Extraction of mangiferin from Mangifera indica leaves using three phase partitioning coupled with ultrasound
Kulkarni VM and Rathod VK
Industrial Crops and Products, 52, 292-297 (2014)
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