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Merck
CN

M4139

S-甲基谷胱甘肽

>98% (TLC), suitable for cell culture

别名:

L-γ-glutamyl-S-methyl-L-cysteinyl-glycine

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关于此项目

经验公式(希尔记法):
C11H19N3O6S
化学文摘社编号:
分子量:
321.35
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.26
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产品名称

S-甲基谷胱甘肽,

方案

>98% (TLC)

质量水平

表单

powder

技术

cell culture | mammalian: suitable

颜色

white

储存温度

2-8°C

SMILES字符串

CSCC(NC(=O)CCC(N)C(O)=O)C(=O)NCC(O)=O

InChI

1S/C11H19N3O6S/c1-21-5-7(10(18)13-4-9(16)17)14-8(15)3-2-6(12)11(19)20/h6-7H,2-5,12H2,1H3,(H,13,18)(H,14,15)(H,16,17)(H,19,20)

InChI key

QTQDDTSVRVWHMO-UHFFFAOYSA-N

一般描述

Useful as a glyoxylase inhibitor.

生化/生理作用

S-methylglutathione is a methionine containing peptide and glyoxylase inhibitor.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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João Costa Pessoa et al.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 7(3), 225-240 (2002-04-06)
The equilibria in the system V(IV)O(2+)-glutathione in aqueous solution were studied in the pH range 2-11 by a combination of pH-potentiometry and spectroscopy (EPR, visible absorption and circular dichroism). The results of the various methods are consistent and the equilibrium
A M Caccuri et al.
The Italian journal of biochemistry, 40(5), 304-311 (1991-09-01)
The binding of the GSH to the GSH transferase pi quenches the protein intrinsic fluorescence more than the binding of GS-Me. The calculated dissociation constants are 38.6 microM and 90.9 microM for GSH and GS-Me, respectively. From the reported data
Alice Rothnie et al.
Molecular pharmacology, 74(6), 1630-1640 (2008-09-05)
Multidrug resistance protein 1 (MRP1/ABCC1) is an ATP-dependent polytopic membrane protein that transports many anticancer drugs and organic anions. Its transport mechanism is multifaceted, especially with respect to the participation of GSH. For example, vincristine is cotransported with GSH, estrone
C Sherrill et al.
Journal of bacteriology, 180(6), 1454-1459 (1998-03-27)
Glutathione (gamma-GluCysGly, GSH) is not found in most gram-positive bacteria, but some appear to synthesize it and others, including Streptococcus mutans ATCC 33402, import it from their growth medium. Import of oxidized glutathione (GSSG) by S. mutans 33402 in 7H9
K S Prabhu et al.
The Biochemical journal, 360(Pt 2), 345-354 (2001-11-22)
A 25 kDa subunit of glutathione S-transferase (GST) from sheep liver microsomes (microsomal GSTA1-1) with a significant selenium-independent glutathione peroxidase activity has been isolated and characterized. Several analytical criteria, including EDTA stripping, protease protection assay and extraction with alkaline Na(2)CO(3)

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