生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen ~65 kDa
种属反应性
human
浓度
0.5 mg/mL
技术
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 using human cancer tissue
indirect ELISA: 1:1,000
western blot: 1:100-1:500 using A375 lysate
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... MMP14(4323)
一般描述
Matrix metalloproteinase-14 (MMP-14) is a collagenase localized to the cell membrane. The gene encoding it is present on human chromosome 14.
免疫原
synthetic peptide corresponding to amino acids 185-299 in the N-terminal region of human matrix metalloproteinase-14 (membrane-type matrix metalloproteinase-1), conjugated to KLH.
应用
Anti-matrix metalloproteinase-14, N-terminal antibody produced in rabbit has been used for western blotting at a dilution of 1:100.
生化/生理作用
Matrix metalloproteinase-14 (MMP-14) aids in the migration of leukocytes and breaks down collagen. Migration of cells through the extracellular matrix is also mediated by it. MMP-14 has been shown to be associated with tuberculosis and glioma.
外形
Solution in phosphate buffered saline containing 0.09% (w/v) sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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