M6036
肌红蛋白 来源于人类心脏
≥95% (SDS-PAGE), buffered aqueous glycerol solution
一般描述
肌红蛋白是一种与血红素相关的低分子量蛋白质。它主要存在于心肌和骨骼肌中。
应用
人心脏肌红蛋白已用作阴性对照品，以监测储存过程中isoAsp的形成。在研究中也被用作抗原，以识别由未免疫小鼠株血清自身抗体识别的自身抗原。
使用人心脏肌红蛋白以通过ESI-TOF MS研究铂（II）9-氨基吖啶复合物与蛋白质和寡核苷酸的相互作用。它也用于使用Stratus Cs荧光计评估血浆肌红蛋白。
生化/生理作用
肌红蛋白可有助于增加扩散，并在氧化肌中储存O2。在肌肉剧烈运动时出现血液供氧不足时，它可瞬间充当供氧库进行供氧。
外形
溶液溶于20 mM Tris-HCl、1 mM EDTA和50%甘油，pH 8.5、2 mg蛋白/mL（Lowry法）
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Signe Helbo et al.
PloS one, 9(5), e97012-e97012 (2014-06-01)
The discovery that cysteine (Cys) S-nitrosation of trout myoglobin (Mb) increases heme O2 affinity has revealed a novel allosteric effect that may promote hypoxia-induced nitric oxide (NO) delivery in the trout heart and improve myocardial efficiency. To better understand this
P Couck et al.
Acta clinica Belgica, 60(2), 75-78 (2005-08-09)
Circulating myoglobin is recognized as an early and sensitive marker of acute coronary diseases. Long turnaround time of myoglobin assays jeopardize their clinical utility. We evaluated the analytical performance of the Stratus CS fluorometric enzyme immunoassay based on dendrimer technology
Iron metabolism and its disorders
Clinical biochemistry of domestic animals, 259-285 (2008)
A High-Throughput Bioluminescent Assay to Monitor the Deamidation of Asparagine and Isomerization of Aspartate Residues in Therapeutic Proteins and Antibodies
Hsiao K, et al.
Journal of Pharmaceutical Sciences, 106(6), 1528-1537 (2017)
Autoantibody patterns in diabetes-prone NOD mice and in standard C57BL/6 mice
Quintana F J and Cohen I R
Journal of Autoimmunity, 17(3), 191-197 (2001)
Chromatograms
application for HPLC我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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