M6190
抗-MYOD1单克隆抗体 小鼠抗
clone 5.2F, purified immunoglobulin, buffered aqueous solution
别名:
抗-肌源性分化抗原1
登录 查看组织和合同定价。
选择尺寸
关于此项目
Conjugate:
unconjugated
Clone:
5.2F, monoclonal
Application:
ICC, IHC (f), IHC (p), IP, WB
Citations:
8
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
5.2F, monoclonal
form
buffered aqueous solution
mol wt
antigen 34 kDa
species reactivity
human, rat, chicken, mouse
concentration
1.0 mg/mL
technique(s)
immunocytochemistry: suitable, immunohistochemistry (formalin-fixed, paraffin-embedded sections): 2-4 μg/mL, immunohistochemistry (frozen sections): 2-4 μg/mL, immunoprecipitation (IP): 2 μg using 1 mg protein lysate, western blot: 1 μg/mL (reacts with the ~45 kDa protein)
isotype
IgG2a
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... MYOD1(4654)
mouse ... Myod1(17927)
rat ... Myod1(337868)
General description
成肌分化抗原1(MYOD1)是一种在骨骼肌中表达的核蛋白。它是碱性螺旋-环-螺旋蛋白(bHLH)转录因子家族的一员。编码它的基因位于人染色体11上。
Immunogen
重组小鼠 MyoD1 蛋白。
Application
小鼠中生产的单克抗-MYOD1 抗体已被用于:
- 1:50 稀释度下进行免疫荧光染色
- 免疫印迹
- 1:300 稀释度下进行免疫染色
Biochem/physiol Actions
成肌分化抗原1(MYOD1)可能参与将乙酰转移酶和甲基转移酶等酶招募到人类基因组中的成肌增强子上。它参与肌肉的再生并通过激活细胞周期停滞来介导肌肉细胞分化。
Physical form
在含有 0.08% 叠氮化钠的磷酸盐缓冲盐水中的溶液。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
未找到合适的产品？
试试我们的产品选型工具.
存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
Roy Blum
Journal of cellular biochemistry, 115(11), 1855-1867 (2014-06-07)
The early 1980s revelation of cis-acting genomic elements, known as transcriptional enhancers, is still regarded as one of the fundamental discoveries in the genomic field. However, only with the emergence of genome-wide techniques has the genuine biological scope of enhancers
Bolin Cai et al.
Cellular & molecular biology letters, 29(1), 9-9 (2024-01-05)
Skeletal muscle development is pivotal for animal growth and health. Recently, long noncoding RNAs (lncRNAs) were found to interact with chromatin through diverse roles. However, little is known about how lncRNAs act as chromatin-associated RNAs to regulate skeletal muscle development.
Shujie Chen et al.
Bio-protocol, 9(14), e3313-e3313 (2019-07-20)
Myofiber isolation followed with ex vivo culture could recapitulate and visualize satellite cells (SCs) activation, proliferation, and differentiation. This approach could be taken to understand the physiology of satellite cells and the molecular mechanism of regulatory factors, in terms of
Bahar Shahidi et al.
JOR spine, 3(2), e1087-e1087 (2020-07-03)
Many chronic musculoskeletal conditions are associated with loss of muscle volume and quality, resulting in functional decline. While atrophy has long been implicated as the mechanism of muscle loss in these conditions, recent evidence has emerged demonstrating a degenerative phenotype
Jennifer A Tinklenberg et al.
Journal of neuropathology and experimental neurology, 78(2), 130-139 (2019-01-01)
Mutations in at least 12 genes are responsible for a group of congenital skeletal muscle diseases known as nemaline myopathies (NMs). NMs are associated with a range of clinical symptoms and pathological changes often including the presence of cytoplasmic rod-like
相关内容
Instructions
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持