生物来源
mouse
质量水平
偶联物
unconjugated
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
5.2F, monoclonal
表单
buffered aqueous solution
分子量
antigen 34 kDa
种属反应性
human, rat, chicken, mouse
浓度
1.0 mg/mL
技术
immunocytochemistry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 2-4 μg/mL
immunohistochemistry (frozen sections): 2-4 μg/mL
immunoprecipitation (IP): 2 μg using 1 mg protein lysate
western blot: 1 μg/mL (reacts with the ~45 kDa protein)
同位素/亚型
IgG2a
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... MYOD1(4654)
mouse ... Myod1(17927)
rat ... Myod1(337868)
一般描述
成肌分化抗原1(MYOD1)是一种在骨骼肌中表达的核蛋白。它是碱性螺旋-环-螺旋蛋白(bHLH)转录因子家族的一员。编码它的基因位于人染色体11上。
免疫原
重组小鼠 MyoD1 蛋白。
应用
小鼠中生产的单克抗-MYOD1 抗体已被用于:
- 1:50 稀释度下进行免疫荧光染色
- 免疫印迹
- 1:300 稀释度下进行免疫染色
生化/生理作用
成肌分化抗原1(MYOD1)可能参与将乙酰转移酶和甲基转移酶等酶招募到人类基因组中的成肌增强子上。它参与肌肉的再生并通过激活细胞周期停滞来介导肌肉细胞分化。
外形
在含有 0.08% 叠氮化钠的磷酸盐缓冲盐水中的溶液。
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
此项目有
Shujie Chen et al.
Bio-protocol, 9(14), e3313-e3313 (2019-07-20)
Myofiber isolation followed with ex vivo culture could recapitulate and visualize satellite cells (SCs) activation, proliferation, and differentiation. This approach could be taken to understand the physiology of satellite cells and the molecular mechanism of regulatory factors, in terms of
Bolin Cai et al.
Cellular & molecular biology letters, 29(1), 9-9 (2024-01-05)
Skeletal muscle development is pivotal for animal growth and health. Recently, long noncoding RNAs (lncRNAs) were found to interact with chromatin through diverse roles. However, little is known about how lncRNAs act as chromatin-associated RNAs to regulate skeletal muscle development.
Xiangyu Sui et al.
Frontiers in oncology, 12, 1040112-1040112 (2022-11-18)
Skeletal muscle atrophy is the major hallmark of cancer cachexia. The mechanisms underlying muscle wasting remain elusive in cachectic patients. Our research seeks to identify differentially expressed genes (DEGs) between non-cachectic and cachectic cancer patients and elucidate their functions. We
Bahar Shahidi et al.
JOR spine, 3(2), e1087-e1087 (2020-07-03)
Many chronic musculoskeletal conditions are associated with loss of muscle volume and quality, resulting in functional decline. While atrophy has long been implicated as the mechanism of muscle loss in these conditions, recent evidence has emerged demonstrating a degenerative phenotype
Ramesh P Arasaradnam et al.
BMC research notes, 5, 240-240 (2012-05-18)
DNA methylation of promoter-associated CpG islands of certain genes may play a role in the development of colorectal cancer. The MYOD-1 gene which is a muscle differentiation gene has been showed to be significantly methylated in colorectal cancer which, is
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