M6546
（±）-2-（对甲氧基苯氧基）丙酸
solid, ≥98%
别名:
PMP
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关于此项目
经验公式（希尔记法）:
C10H12O4
化学文摘社编号:
分子量:
196.20
MDL编号:
UNSPSC代码:
12352202
PubChem化学物质编号:
NACRES:
NA.77
产品名称
（±）-2-（对甲氧基苯氧基）丙酸, ≥98%
生物来源
synthetic (organic)
质量水平
方案
≥98%
表单
solid
SMILES字符串
COc1ccc(OC(C)C(O)=O)cc1
InChI
1S/C10H12O4/c1-7(10(11)12)14-9-5-3-8(13-2)4-6-9/h3-7H,1-2H3,(H,11,12)
InChI key
MIEKOFWWHVOKQX-UHFFFAOYSA-N
应用
(±)-2-(对甲氧基苯氧基)丙酸可作为甜味受体拮抗剂，研究其对大鼠糖诱导胰高血糖素样肽1（GLP-1）分泌的影响。它也可用于研究分泌素肿瘤细胞系（STC-1）在(±)-2-(对甲氧基苯氧基)丙酸或乳清存在及不存在环境下对甜味剂的反应。
生化/生理作用
作为一种味觉调节剂，钠盐可以抑制人对甜味的感知，但对大鼠却没有影响。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
A Sclafani et al.
Physiology & behavior, 61(1), 25-29 (1997-01-01)
Cypha, propionic acid, 2-(4-methoxyphenol) salt, is a commercially available sweet taste inhibitor used in food products. The present study examined whether or not Cypha blocked the sweet taste response of rats. This was accomplished by measuring the consummatory response of
Masaki Hayakawa et al.
Biochemical and biophysical research communications (2018-02-07)
Glucagon-like peptide 1 (GLP-1), an incretin gastrointestinal hormone, is secreted when stimulated by nutrients including metabolizable sugars such as glucose and fructose. d-Allulose (allulose), also known as d-psicose, is a C-3 isomer of d-fructose and a rare sugar with anti-diabetic
Zhihao Zhang et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 84, 1350-1358 (2016-11-03)
Dendrobium officinale Kimura et Migo (Dendrobium catenatum Lindley), a prized traditional Chinese Medicine, has been used in China and Southeast Asian countries for centuries. The present study was aimed to investigate the effects and the possible mechanisms of the Dendrobium
Kensuke Ninomiya et al.
The EMBO journal, 39(3), e102729-e102729 (2019-11-30)
A number of long noncoding RNAs (lncRNAs) are induced in response to specific stresses to construct membrane-less nuclear bodies; however, their function remains poorly understood. Here, we report the role of nuclear stress bodies (nSBs) formed on highly repetitive satellite
Almudena Aguilera-Diaz et al.
PloS one, 15(1), e0227986-e0227986 (2020-01-25)
The diagnosis of myeloid neoplasms (MN) has significantly evolved through the last few decades. Next Generation Sequencing (NGS) is gradually becoming an essential tool to help clinicians with disease management. To this end, most specialized genetic laboratories have implemented NGS
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