M6546
（±）-2-（对甲氧基苯氧基）丙酸
solid, ≥98%
别名:
PMP
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关于此项目
经验公式（希尔记法）:
C10H12O4
化学文摘社编号:
分子量:
196.20
MDL编号:
UNSPSC代码:
12352202
PubChem化学物质编号:
NACRES:
NA.77
产品名称
（±）-2-（对甲氧基苯氧基）丙酸, ≥98%
生物来源
synthetic (organic)
方案
≥98%
表单
solid
SMILES字符串
COc1ccc(OC(C)C(O)=O)cc1
InChI
1S/C10H12O4/c1-7(10(11)12)14-9-5-3-8(13-2)4-6-9/h3-7H,1-2H3,(H,11,12)
InChI key
MIEKOFWWHVOKQX-UHFFFAOYSA-N
应用
(±)-2-(对甲氧基苯氧基)丙酸可作为甜味受体拮抗剂，研究其对大鼠糖诱导胰高血糖素样肽1（GLP-1）分泌的影响。它也可用于研究分泌素肿瘤细胞系（STC-1）在(±)-2-(对甲氧基苯氧基)丙酸或乳清存在及不存在环境下对甜味剂的反应。
生化/生理作用
作为一种味觉调节剂，钠盐可以抑制人对甜味的感知，但对大鼠却没有影响。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
A Sclafani et al.
Physiology & behavior, 61(1), 25-29 (1997-01-01)
Cypha, propionic acid, 2-(4-methoxyphenol) salt, is a commercially available sweet taste inhibitor used in food products. The present study examined whether or not Cypha blocked the sweet taste response of rats. This was accomplished by measuring the consummatory response of
David E Lanfear et al.
JACC. Heart failure, 5(11), 823-832 (2017-11-04)
This study sought to derive and validate plasma metabolite associations with survival in heart failure (HF) patients. Profiling of plasma metabolites to predict the course of HF appears promising, but validation and incremental value of these profiles are less established. Patients
Paolo Tommasino et al.
Frontiers in neurorobotics, 11, 65-65 (2017-12-19)
A major challenge in robotics and computational neuroscience is relative to the posture/movement problem in presence of kinematic redundancy. We recently addressed this issue using a principled approach which, in conjunction with nonlinear inverse optimization, allowed capturing postural strategies such
Li-Chun Chen et al.
Food chemistry, 212, 768-777 (2016-07-05)
The biological functions of cell membranes strongly influence the binding and transport of molecular species. We developed STC-1 cell line stably expressing the sweet taste receptor (T1R2/T1R3), and explored the possible correlation between sweeteners and membrane dipole potential of STC-1
Lilli Saarinen et al.
PloS one, 12(4), e0174898-e0174898 (2017-04-21)
Pseudomyxoma peritonei (PMP) is a subtype of mucinous adenocarcinoma mainly restricted to the peritoneal cavity and most commonly originating from the appendix. The genetic background of PMP is poorly understood and no targeted treatments are currently available for this fatal
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