M7522
2-巯基乙醇
liquid, BioReagent, suitable for cell culture
别名:
β-巯基乙醇, 2-羟乙基硫醇, BME, 硫代二甘醇
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线性分子式:
HSCH2CH2OH
化学文摘社编号:
分子量:
78.13
EC Number:
200-464-6
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
773648
MDL number:
InChI key
DGVVWUTYPXICAM-UHFFFAOYSA-N
InChI
1S/C2H6OS/c3-1-2-4/h3-4H,1-2H2
SMILES string
OCCS
vapor density
2.69 (vs air)
vapor pressure
1 mmHg ( 20 °C)
product line
BioReagent
form
liquid
expl. lim.
18 %
concentration
14.3 M (pure liquid)
technique(s)
cell culture | mammalian: suitable
bp
157 °C (lit.)
solubility
H2O: 1 mL/mL
density
1.114 g/mL at 25 °C (lit.)
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Application
BME is suitable for reducing protein disulfide bonds prior to polyacrylamide gel electrophoresis and is usually included in a sample buffer for SDS-PAGE at a concentration of 5%. Cleaving intermolecular (between subunits) disulfide bonds allows the subunits of a protein to separate independently on SDS-PAGE. Cleaving intramolecular (within subunit) disulfide bonds allows the subunits to become completely denatured so that each peptide migrates according to its chain length with no influence due to secondary structure.
signalword
Danger
Hazard Classifications
Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1A - STOT RE 2 Oral
target_organs
Liver,Heart
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
flash_point_f
165.2 °F - closed cup
flash_point_c
74 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
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