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Merck
CN

MAK108

磷脂转运蛋白活性检测试剂盒

Supplied by Roar Biomedical, Inc.

别名:

磷脂转运蛋白活性检测试剂盒

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NACRES:
NA.84
UNSPSC Code:
12161503
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usage

sufficient for 100 fluorometric tests

application(s)

pharmaceutical

detection method

fluorometric

relevant disease(s)

cardiovascular diseases

storage temp.

2-8°C

Gene Information

human ... PLTP(5360)

General description

Phospholipid transfer protein (PLTP) is a protein present in normal human plasma. PLTP transfers phospholipids among lipoproteins in plasma.

Application

Suitable to determine Phospholipid transfer protein (PLTP) activity in plasma or serum (fresh or frozen) as well as other sources of PLTP.

Biochem/physiol Actions

The PLTP Activity Assay Kit includes proprietary substrates to detect PLTP mediated transfer of fluorescent substrate. Transfer activity results in increased fluorescent emission intensity (λEx = 465 nm/λEm = 535 nm) from the assay.

存储类别

10 - Combustible liquids

wgk

WGK 1

法规信息

新产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. Are products MAK107 and MAK108 compatible with mouse serum?

    Yes, but please be aware of possible sample hemolysis. Depending on the method of mouse sample collection, hemolysis may be common, which can interfere with fluorescence emission via color quenching.

  6. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Ryan J Henderson et al.
Drug development and industrial pharmacy, 35(9), 1139-1146 (2009-04-22)
To investigate how different formulations of Amphotericin-B (Amp-B) affect the activity of phospholipid transfer protein (PLTP) when incubated with hyperlipidemic and normolipidemic plasma at physiological temperature (37 degrees C). Six hyperlipidemic and six normolipidemic plasma samples were collected and tested
Axel Schlitt et al.
American journal of nephrology, 27(2), 138-143 (2007-02-20)
Phospholipid transfer protein (PLTP) is mainly involved in high-density lipoprotein (HDL) metabolism. The role of PLTP in atherogenesis is still controversial. We aimed to investigate PLTP activity in hemodialysis (HD) patients, a population which has an increased risk for the
Suheeta Roy et al.
Hepatology (Baltimore, Md.), 41(4), 887-895 (2005-03-29)
Human obesity is associated with abnormal hepatic cholesterol homeostasis and resistance to leptin action. Because leptin administration to rodents promotes the biliary elimination of plasma cholesterol, this study was designed to elucidate a pathophysiological role for leptin during the development
Alexis Klein et al.
Arteriosclerosis, thrombosis, and vascular biology, 26(9), 2160-2167 (2006-07-11)
The aim of the present study was to assess the effect of alpha-tocopherol, the main vitamin E isomer on phosphatidylserine (PS) exposure at the surface of circulating erythrocytes, and to determine consequences on erythrocyte properties. In vitro alpha-tocopherol enrichment of
Thomas Gautier et al.
The Journal of biological chemistry, 283(27), 18702-18710 (2008-05-07)
Lipopolysaccharides (LPS) are components of Gram-negative bacteria. The cellular response from the host to LPS is mediated through stepwise interactions involving the lipopolysaccharide-binding protein (LBP), CD14, and MD-2, which produces the rearrangement of TLR4. In addition to LBP, the lipid

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