N151
Nisoxetine hydrochloride
≥98% (HPLC), Norepinephrine reuptake inhibitor, solid
别名:
(±)-γ-(2-Methoxyphenoxy)-N-methyl-benzenepropanamine hydrochloride, LY-94,939
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关于此项目
经验公式（希尔记法）:
C17H21NO2 · HCl
化学文摘社编号:
分子量:
307.82
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Storage condition:
desiccated
产品名称
Nisoxetine hydrochloride, solid, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
solid
storage condition
desiccated
color
white to beige
solubility
H2O: 20 mg/mL, ethanol: 50 mg/mL
SMILES string
Cl[H].CNCCC(Oc1ccccc1OC)c2ccccc2
InChI
1S/C17H21NO2.ClH/c1-18-13-12-15(14-8-4-3-5-9-14)20-17-11-7-6-10-16(17)19-2;/h3-11,15,18H,12-13H2,1-2H3;1H
InChI key
LCEURBZEQJZUPV-UHFFFAOYSA-N
Application
Nisoxetine has been used as a norepinephrine transport (NET) blocker in autoradiography studies. It has also been used as a NET blocker to study its effects on perivascular adipose tissue.
Biochem/physiol Actions
Nisoxetine is a selective and potent noradrenaline reuptake inhibitor. It has a high affinity towards the noradrenaline transporter. Nisoxetine possesses antidepressant activity.
Features and Benefits
This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)