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N6136

Sigma-Aldrich

氯化镍(II) 六水合物

BioReagent, suitable for cell culture

别名:

NiCl2.6H2O, Nickel chloride hexahydrate, Nickel dichloride hexahydrate

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25 G
¥234.05
100 G
¥384.49
500 G
¥1,569.17

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25 G
¥234.05
100 G
¥384.49
500 G
¥1,569.17

About This Item

线性分子式:
NiCl2 · 6H2O
CAS Number:
分子量:
237.69
MDL编号:
UNSPSC代码:
12352207
PubChem化学物质编号:
NACRES:
NA.71

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产品线

BioReagent

质量水平

表单

powder

技术

cell culture | mammalian: suitable

SMILES字符串

[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].Cl[Ni]Cl

InChI

1S/2ClH.Ni.6H2O/h2*1H;;6*1H2/q;;+2;;;;;;/p-2

InChI key

LAIZPRYFQUWUBN-UHFFFAOYSA-L

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此商品
F3606653586F3401
4-氟苯胺 99%

F3800

4-氟苯胺

3-氟苯胺 99%

F3606

3-氟苯胺

2-氟苯胺 ≥99%

F3401

2-氟苯胺

assay

99%

assay

99%

assay

97%

assay

≥99%

form

liquid

form

liquid

form

-

form

-

density

1.173 g/mL at 25 °C (lit.)

density

1.156 g/mL at 25 °C (lit.)

density

-

density

1.151 g/mL at 25 °C (lit.)

bp

187 °C/767 mmHg (lit.)

bp

186 °C/756 mmHg (lit.)

bp

-

bp

182-183 °C (lit.)

refractive index

n20/D 1.539 (lit.)

refractive index

n20/D 1.542 (lit.)

refractive index

-

refractive index

n20/D 1.544 (lit.)

应用

六水氯化镍 (II):
  • 用于制备镍镀层溶液,用于在合成多壁碳纳米管微电机过程中还原碳层内部对镍进行静电镀膜 [1]
  • 用于筛选金属对血管内皮细胞的炎症效应 [2]
  • 作为人工脑脊液(ACSF)的添加剂,用于分析海马脑片中兴奋性突触后电流(EPSPs)[3]

生化/生理作用

镍 (Ni) 是人体必需的微量元素,对 DNA、RNA 和蛋白质的结构和功能均具有重要作用。其在较高浓度时对肾、肺及心血管系统有毒性作用。[4]镍与致癌作用有关。[5]Ni 2 + 离子是一种诱裂剂。[6]镍离子 (Ni2 + ) 是一种非特异性电压门控钙通道阻滞剂。[7]

警示用语:

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A Inhalation - Muta. 2 - Repr. 1B - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1 Inhalation

靶器官

Lungs

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

危险化学品
  • 技术规格说明书

  • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number

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    C V Eadsforth et al.
    Xenobiotica; the fate of foreign compounds in biological systems, 16(6), 555-566 (1986-06-01)
    o-Fluoroaniline is rapidly metabolized and excreted in rats, rabbits and marmosets. Following a single oral dose of 14C-fluoroaniline of about 20 mg/kg, more than 80% of the dose is excreted in 0-24 h, the urine being the major route of
    Meizhen Wang et al.
    Environmental science and pollution research international, 20(9), 6201-6209 (2013-04-17)
    To develop a bacterial bioaugmentation system for fluorine-containing industrial wastewater treatment, optimal conditions for 4-fluoroaniline (4-FA) degradation and autoinducer release in Acinetobacter sp. TW were determined. Quorum sensing in biofilms of strain TW was also investigated. Different optimal conditions exist
    G B Scarfe et al.
    Xenobiotica; the fate of foreign compounds in biological systems, 29(2), 205-216 (1999-04-13)
    1. The urinary metabolic fate of 4-fluoroaniline (4-FA) and 1-[13C]-4-fluoroacetanilide (4-FAA) has been studied using NMR-based methods after 50 and 100 mg kg(-1) i.p. doses respectively to the male Sprague-Dawley rat. 2. 4-FA was both ortho- and para-hydroxylated. The major
    I M Rietjens et al.
    Chemico-biological interactions, 77(3), 263-281 (1991-01-01)
    Metabolism and bioactivation of fluoroanilines was studied both in vitro in microsomal systems and in vivo. 4-Fluoroaniline and pentafluoroaniline and their non-para fluorinated analogues were used as the model compounds. Special attention was focussed on bioactivation to reactive benzoquinoneimines. Cytochrome
    J G Bundy et al.
    Xenobiotica; the fate of foreign compounds in biological systems, 32(6), 479-490 (2002-08-06)
    1. Little is known about metabolism of xenobiotics by earthworms, despite their importance in soil ecotoxicity testing. Normal earthworms and earthworms treated with antibiotics to ensure inhibition of gut microflora were exposed to two model xenobiotic compounds, 4-fluoroaniline and 4-fluorobiphenyl

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