N6877
L-正亮氨酸
≥98% (TLC)
别名:
(S)-(+)-2-氨基己酸, (S)-2-氨基己酸
质量水平
方案
≥98% (TLC)
表单
powder
颜色
white
mp
>300 °C (lit.)
应用
detection
SMILES字符串
CCCC[C@H](N)C(O)=O
InChI
1S/C6H13NO2/c1-2-3-4-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)/t5-/m0/s1
InChI key
LRQKBLKVPFOOQJ-YFKPBYRVSA-N
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应用
- l-去甲亮氨酸对高糖诱导的胰岛素敏感性和骨骼肌细胞线粒体功能的影响。该研究探讨了l -去甲亮氨酸对胰岛素敏感性和线粒体功能的有益作用，强调了其在代谢途径研究和通过靶向氨基酸治疗治疗糖尿病中的应用潜力（Ding et al., 2024）。
生化/生理作用
L-正亮氨酸是一种通常用作内标的合成氨基酸。
其他说明
非必需氨基酸
警示用语：
Warning
危险声明
危险分类
Skin Sens. 1
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Luana Bontempo et al.
Food chemistry, 318, 126426-126426 (2020-03-07)
Until now, there has been a lack of analytical methods that can reliably verify the authenticity of organically grown plants and derived organic food products. In this study, stable isotope ratio analysis of hydrogen (H, δ2H), carbon (C, δ13C), nitrogen
Yu-Ying Yang et al.
Chemistry & biology, 17(11), 1212-1222 (2010-11-26)
The advances in bioorthogonal ligation methods have provided new opportunities for proteomic analysis of newly synthesized proteins, posttranslational modifications, and specific enzyme families using azide/alkyne-functionalized chemical reporters and activity-based probes. Efficient enrichment and elution of azide/alkyne-labeled proteins with selectively cleavable
Stefanie Geissler et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 78(1), 75-82 (2011-01-11)
Maltosine, a 3-hydroxy-4-pyridinone derivative of lysine formed in the course of the advanced Maillard reaction, is an effective metal chelating agent. It therefore represents an interesting compound for the treatment of metal ion storage diseases. We synthesized 6-(3-hydroxy-4-oxo-2-methyl-4(1H)-pyridin-1-yl)-l-norleucine (free maltosine)
Silvia Lisa et al.
Cellular and molecular life sciences : CMLS, 67(16), 2825-2838 (2010-05-11)
The conversion of the cellular prion protein (PrP(C)) into its disease-associated form (PrP(Sc)) involves a major conformational change and the accumulation of sulfoxidized methionines. Computational and synthetic approaches have shown that this change in the polarity of M206 and M213
Alborz Mahdavi et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(1), 433-438 (2013-12-19)
Pathogenic microbes have evolved complex secretion systems to deliver virulence factors into host cells. Identification of these factors is critical for understanding the infection process. We report a powerful and versatile approach to the selective labeling and identification of secreted
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