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经验公式(希尔记法):
C14H18N2O8
化学文摘社编号:
分子量:
342.30
UNSPSC Code:
12352204
NACRES:
NA.28
PubChem Substance ID:
EC Number:
239-024-3
Beilstein/REAXYS Number:
96194
MDL number:
产品名称
4-硝基苯基-N-乙酰-β-D-半乳糖胺, ≥98%
InChI key
OMRLTNCLYHKQCK-RKQHYHRCSA-N
InChI
1S/C14H18N2O8/c1-7(18)15-11-13(20)12(19)10(6-17)24-14(11)23-9-4-2-8(3-5-9)16(21)22/h2-5,10-14,17,19-20H,6H2,1H3,(H,15,18)/t10-,11-,12+,13-,14-/m1/s1
SMILES string
CC(=O)N[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1Oc2ccc(cc2)[N+]([O-])=O
assay
≥98%
form
powder
solubility
DMF: 50 mg/mL
storage temp.
−20°C
Quality Level
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Application
4-硝基苯基-N-乙酰基-β-D-半乳糖胺已被:
- 用作假结核耶尔森氏菌蛋白的糖基水解酶测定中的合成底物
- 用作人类肺腺癌基底上皮细胞A549中-β-己糖胺酶测定的底物
- 用作大鼠肾脏组织提取物中N-乙酰-β-D-半乳糖苷酶测定的底物
General description
4-硝基苯基-N-乙酰基-β-D-半乳糖胺是N-乙酰基-β-D-半乳糖苷酶和d N-乙酰基-β-D-己糖胺酶的发色底物。它具有膜透过性性,可作为高尔基囊泡中6-磺基转移酶的底物。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Lysosomal enzymes are decreased in the kidney of diabetic rats
Peres GB, et al.
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Involvement of lysosomal exocytosis in the excretion of mesoporous silica nanoparticles and enhancement of the drug delivery effect by exocytosis inhibition
Yanes RE, et al.
Small, 9(5), 697-704 (2013)
Heterologous expression and characterization of an N-acetyl-beta-D-hexosaminidase from Lactococcus lactis ssp. lactis IL1403
Nguyen HA, et al.
Journal of Agricultural and Food Chemistry, 60(12), 3275-3281 (2012)
Loss of a biofilm-inhibiting glycosyl hydrolase during the emergence of Yersinia pestis
Erickson DL, et al.
Journal of Bacteriology, 190(24), 8163-8170 (2008)
S K Chatterjee et al.
Cancer, 49(1), 128-135 (1982-01-01)
Levels and isoenzyme profiles of beta-hexosaminidase were compared in extracts from normal ovarian and ovarian epithelial tumors. The specific activities of beta-hexosaminidase were significantly (P less than 0.001) higher in malignant than in normal ovarian tissues. The enzyme levels of
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