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Merck
CN

P0109

植酸 钠盐 水合物

from rice, ≥90% phosphorus (P) basis

别名:

InsP6, 肌醇六(磷酸二氢酯), 肌醇六磷酸

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关于此项目

经验公式(希尔记法):
C6H18O24P6 · xNa+ · yH2O
化学文摘社编号:
分子量:
660.04 (anhydrous free acid basis)
UNSPSC Code:
12352201
EC Number:
238-242-6
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biological source

rice

assay

≥90% phosphorus (P) basis

composition

Sodium, ≥10 mol/mol ICP

impurities

≤0.1% Inorganic phosphorus

SMILES string

[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)O[C@H]1[C@H](OP([O-])([O-])=O)[C@H](OP([O-])([O-])=O)[C@H](OP([O-])([O-])=O)[C@@H](OP([O-])([O-])=O)[C@@H]1OP([O-])([O-])=O

InChI

1S/C6H18O24P6.12Na/c7-31(8,9)25-1-2(26-32(10,11)12)4(28-34(16,17)18)6(30-36(22,23)24)5(29-35(19,20)21)3(1)27-33(13,14)15;;;;;;;;;;;;/h1-6H,(H2,7,8,9)(H2,10,11,12)(H2,13,14,15)(H2,16,17,18)(H2,19,20,21)(H2,22,23,24);;;;;;;;;;;;/q;12*+1/p-12

InChI key

KETSPIPODMGOEJ-UHFFFAOYSA-B

General description

Phytic acid is a major determinant of zinc bioavailability.

Application

Recommended for use as phytase substrate due to low inorganic phosphorus content. Phytic acid has been used as an anti-nutrient factor in a study to assess the effect of processing on the African locust bean. It has also been used in a study to investigate the effect of dietary rice bran component γ-oryzanol on tumor growth.

Biochem/physiol Actions

植酸存在于所有的真核细胞中。 在植物中,它作为其他肌醇磷酸和焦磷酸[PO4]3−储存库和前体。 它的高表面负电使它在体内是二价,三价阳离子的强力螯合剂,很可能和体内Ca2+或Mg2+离子相关。 在酵母中,植酸和细胞核孔蛋白质Gle1共同作用,通过共激活RNA依赖DExD-盒蛋白5(Dbp5)ATP酶活性,调节细胞核MRNA输出.


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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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Nusrat Ali et al.
PloS one, 8(7), e68161-e68161 (2013-07-12)
Phytic acid (InsP(6)) is considered to be the major source of phosphorus and inositol phosphates in most cereal grains. However, InsP(6) is not utilized efficiently by monogastric animals due to lack of phytase enzyme. Furthermore, due to its ability to
Antonio Ariza et al.
PloS one, 8(5), e65062-e65062 (2013-06-07)
Phytases hydrolyse phytate (myo-inositol hexakisphosphate), the principal form of phosphate stored in plant seeds to produce phosphate and lower phosphorylated myo-inositols. They are used extensively in the feed industry, and have been characterised biochemically and structurally with a number of
Ameny Farhat-Khemakhem et al.
AMB Express, 2(1), 10-10 (2012-01-28)
To attempt cost-effective production of US417 phytase in Bacillus subtilis, we developed an efficient system for its large-scale production in the generally recognized as safe microorganism B. subtilis 168. Hence, the phy US417 corresponding gene was cloned in the pMSP3535