P0543
5-Pregnen-3β-ol-20-one-16α-carbonitrile
synthetic (organic), ≥97%, glucocorticoid receptor antagonist, powder, crystals or chunks
别名:
Pregnenolone-16α-carbonitrile
登录 查看组织和合同定价。
选择规格
变更视图
关于此项目
经验公式（希尔记法）:
C22H31NO2
化学文摘社编号:
分子量:
341.49
UNSPSC Code:
51111800
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥97%
Form:
powder, crystals or chunks
产品名称
5-Pregnen-3β-ol-20-one-16α-carbonitrile, ≥97%
biological source
synthetic (organic)
Quality Segment
sterility
non-sterile
assay
≥97%
form
powder, crystals or chunks
technique(s)
cell culture | mammalian: suitable
solubility
chloroform: methanol (1:1): 50 mg/mL, clear, colorless to faintly yellow (with heat)
shipped in
ambient
storage temp.
2-8°C
SMILES string
C[C@@]12[C@](C[C@@H](C#N)[C@@H]2C(C)=O)([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC1
InChI
1S/C22H31NO2/c1-13(24)20-14(12-23)10-19-17-5-4-15-11-16(25)6-8-21(15,2)18(17)7-9-22(19,20)3/h4,14,16-20,25H,5-11H2,1-3H3/t14-,16-,17+,18-,19-,20-,21-,22-/m0/s1
InChI key
VSBHRRMYCDQLJF-ZDNYCOCVSA-N
Application
5-Pregnen-3β-ol-20-one-16α-carbonitrile has been used:
- in the induction of cytochrome P450
- as pregnane X receptor (PXR) activator in human liver cell lines.
Biochem/physiol Actions
Pregnenolone-16a-carbonitrile (PCN) is a glucocorticoid receptor antagonist and a PXR (pregnane X receptor) activator.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
>199.9 °F - closed cup
flash_point_c
> 93.3 °C - closed cup
ppe
Eyeshields, Gloves, type N95 (US)