P1162
棕榈酸N-羟基琥珀酸酯
≥98% (TLC)
别名:
N-琥珀酸酯基棕榈酸酯, N-（棕榈酰氧基）琥珀酸酯, 棕榈酸N-琥珀酸酯
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关于此项目
经验公式（希尔记法）:
C20H35NO4
化学文摘社编号:
分子量:
353.50
Beilstein:
1547411
MDL编号:
UNSPSC代码:
12352211
PubChem化学物质编号:
NACRES:
NA.25
质量水平
方案
≥98% (TLC)
表单
powder
脂质类型
saturated FAs
储存温度
−20°C
SMILES字符串
CCCCCCCCCCCCCCCC(=O)ON1C(=O)CCC1=O
InChI
1S/C20H35NO4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-20(24)25-21-18(22)16-17-19(21)23/h2-17H2,1H3
InChI key
OTNHQVHEZCBZQU-UHFFFAOYSA-N
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应用
棕榈酸N-羟基琥珀酰亚胺酯已被用于偶联蛋白质，以制备靶向递送载体。它还被用于棕榈酸与卵清蛋白的共价连接。
用于合成氨基和硫代化合物的十六酰基衍生物，如氨基酸、氨酰-tRNA、辅酶 a、巯基乙酸等。
生化/生理作用
棕榈酸N-羟基琥珀酰亚胺酯用于蛋白质与棕榈酸的共价连接。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Cell-specific siRNA delivery by peptides and antibodies
Methods in Enzymology, 502, 91-122 (2012)
Preparation of immune stimulating complexes (ISCOMs) as adjuvants
Mowat AM and Reid G
Current Protocols in Immunology, 16(1), 2-11 (1995)
Jinhwan Cho et al.
Journal of controlled release : official journal of the Controlled Release Society, 321, 49-58 (2020-02-02)
Therapeutic proteins are indispensable for treatment of various human diseases. However, intrinsic short serum half-lives of proteins are still big hurdles for developing new therapeutic proteins or expanding applications of existing ones. Urate oxidase (Uox) is a therapeutic protein clinically
Cell-specific siRNA delivery by peptides and antibodies
Test, 502, 91-122 (2012)
Ana Rute Neves et al.
Nanotechnology, 26(49), 495103-495103 (2015-11-18)
Nanotechnology can be an important tool to improve the permeability of some drugs for the blood-brain barrier. In this work we created a new system to enter the brain by functionalizing solid lipid nanoparticles with apolipoprotein E, aiming to enhance
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