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P1306

Peptide YY human

Name: Peptide YY human
Brand: SIGMA

≥97% (HPLC), synthetic

别名:

PYY, Tyr-Pro-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-NH₂

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关于此项目

经验公式（希尔记法）:

C₁₉₄H₂₉₅N₅₅O₅₇

化学文摘社编号:

118997-30-1

分子量:

4309.75

UNSPSC Code:

51111800

NACRES:

NA.32

MDL number:

MFCD00081843

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属性

biological source

synthetic

Quality Level

200

assay

≥97% (HPLC)

form

solid

UniProt accession no.

P10082

storage temp.

−20°C

Gene Information

human ... PYY(5697)

说明

General description

Human peptide YY (PYY) is secreted by mucosal L cells in the distal ileum, colon and rectum. It consists of 36 amino acids. The gene encoding PYY is localized on human chromosome 17q21.1.

Application

Peptide YY human has been used as a supplement in Roswell Park Memorial Institute medium (RPMI medium) to culture pancreatic duct-derived cells.

Biochem/physiol Actions

Human peptide YY (PYY) has a role in food ingestion, gut motility and insulin secretion. The protein suppresses appetite. It has been associated with obesity and type 2 diabetes. PYY also has a role in energy homeostasis.

Gut hormone that inhibits both secretin and cholecystokinin-stimulated pancreatic secretion. Endogenous nonselective agonist at NPY receptors.

Inhibits secretin and cholecystokinin-stimulated pancreatic secretion;endogenous nonselective agonist at NPY receptors.

Other Notes

Lyophilized from 0.1% TFA in H2O

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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分析证书(COA)

Lot/Batch Number

0000433864

0000329564

0000329567

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TLR ligands and butyrate increase Pyy expression through two distinct but inter-regulated pathways.

Larraufie P

Cellular Microbiology (2017)

Genomic and gene expression signature of the pre-invasive
testicular carcinoma in situ

Kristian Almstrup

Cell and Tissue Research (2005)

Rapid and Efficient In Vitro Generation of Pancreatic Islet
Progenitor Cells from Nonendocrine Epithelial Cells in the
Adult Human Pancreas

JOSEPHINE S. D?ALESSANDRO

Stem Cells and Development (2007)

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