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Merck
CN

P1641

5α-孕烷-3β,11β,17α,21-四醇-20-酮

别名:

3β,11β,17α,21-四羟基-5α-孕甾-20-酮, 3β,5α-四氢皮质甾醇, 3β-别四氢皮质甾醇, Reichstein’s substance V

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经验公式(希尔记法):
C21H34O5
化学文摘社编号:
分子量:
366.49
UNSPSC Code:
41116107
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technique(s)

HPLC: suitable, gas chromatography (GC): suitable

format

neat

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

新产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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J Müller-Berghaus et al.
Acta paediatrica (Oslo, Norway : 1992), 85(1), 111-113 (1996-01-01)
We report the case of a 16-month-old boy who presented with chronic vomiting, failure to thrive, arterial hypertension and medullary nephrocalcinosis. Laboratory results revealed hypokalaemia, metabolic alkalosis, increased urinary potassium excretion and a hyporeninaemic hypoaldosteronism. Chromatographic determination of urinary steroid
P W Raven et al.
Endocrine research, 22(4), 811-815 (1996-11-01)
The increased ratio of 5 alpha to 5 beta reduced steroids associated with apparent mineralocorticoid excess (AME) may be a necessary consequence of altered 11 beta-hydroxysteroid dehydrogenase (11-HSD) activity. In order to test this hypothesis we have compared changes in
L M Muller et al.
Journal of steroid biochemistry, 31(6), 979-982 (1988-12-01)
The urinary levels of seven steroids, 5 alpha-androstane-3 alpha,17 beta-diol, 5 beta-androstane-3 alpha,17 beta-diol, androsterone, etiocholanolone, tetrahydrocortisone, tetrahydrocortisol and allotetrahydrocortisol were measured in both normal (n = 18) and hirsute (n = 24) women. The results confirmed 5 alpha-androstane-3 alpha,17
T A Mori et al.
Clinical and experimental pharmacology & physiology, 18(5), 287-290 (1991-05-01)
1. From an earlier cross-sectional survey of 343 public servants, 15 pairs of non-smoking teetotallers and heavy drinkers (alcohol intake more than 350 mL/week) were matched for age and adiposity and utilized for a case-control study of the effects of
P M Stewart et al.
Clinical science (London, England : 1979), 78(1), 49-54 (1990-01-01)
1. 11-beta-Hydroxysteroid dehydrogenase is an enzyme complex consisting of 11 beta-dehydrogenase and 11-oxoreductase responsible for the interconversion of cortisol to cortisone in man. Inhibition of 11 beta-dehydrogenase (e.g. after liquorice ingestion) results in cortisol acting as a potent mineralocorticoid. We

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