P2053
pGlu-Glu-Pro Amide
≥97% (HPLC)
别名:
Fertilization Promoting Peptide
方案
≥97% (HPLC)
储存温度
−20°C
SMILES字符串
NC(=O)C1CCCN1C(=O)C(CCC(O)=O)NC(=O)C2CCC(=O)N2
InChI
1S/C15H22N4O6/c16-13(23)10-2-1-7-19(10)15(25)9(4-6-12(21)22)18-14(24)8-3-5-11(20)17-8/h8-10H,1-7H2,(H2,16,23)(H,17,20)(H,18,24)(H,21,22)
InChI key
HYZBGWLLSXSYLX-UHFFFAOYSA-N
Amino Acid Sequence
Glp-Glu-Pro-NH2
生化/生理作用
TRH analog that is produced in the thyroid, mammary gland and prostate. Promotes fertilization by enhancing sperm function.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Patricia M Hinkle et al.
Brain research, 935(1-2), 59-64 (2002-06-14)
A large family of TRH-like peptides in the limbic region of rat brain including pGlu-Glu-Pro-NH(2) (EEP), pGlu-Val-Pro-NH(2) (Val(2)-TRH), Leu(2)-TRH, Phe(2)-TRH and Tyr(2)-TRH has recently been discovered. TRH (pGlu-His-Pro-NH(2)) has antidepressant, neuroprotective, analeptic, anticonvulsant, antiamnesic and euphoric properties, and other TRH-like
Stephan Schilling et al.
Biological chemistry, 384(12), 1583-1592 (2004-01-15)
Glutaminyl cyclases (QC) catalyze the intramolecular cyclization of N-terminal glutamine residues of peptides and proteins. For a comparison of the substrate specificity of human and papaya QC enzymes, a novel continuous assay was established by adapting an existing discontinuous method.
L D Safronova et al.
Ontogenez, 33(3), 165-169 (2002-06-19)
The mechanisms underlying normal spermatogenesis and its pathology expressed as male sterility determined by t-complex located on chromosome 17 in mice are considered in this review. t-Complex is a very convenient model with diverse markers of expression of the genes
Lynn R Fraser et al.
The Journal of reproduction and development, 51(1), 37-46 (2005-03-08)
When released into an appropriate environment, mammalian spermatozoa begin to capacitate and then continue until fully capacitated and able to fertilize. During capacitation in vitro, some cells 'over-capacitate' and undergo spontaneous acrosome reactions; this would be highly undesirable in vivo
Lynn R Fraser et al.
Human reproduction (Oxford, England), 19(3), 596-606 (2004-03-05)
Fertilization-promoting peptide (FPP), angiotensin II (AII) and calcitonin, present in seminal plasma, have significant effects on mouse sperm function in vitro. This study investigated responses of uncapacitated and capacitated human sperm to these peptides, initially using samples from donors with
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