P3136
Polydeoxyguanylic acid · Polydeoxycytidylic acid sodium salt
double-stranded homopolymer
别名:
Poly(dG) • Poly(dC)
表单
solid
储存温度
−20°C
应用
Polydeoxyguanylic acid • Polydeoxycytidylic acid (Poly(dG) • Poly(dC)) is a high molecular weight double-stranded homopolymer DNA model compound used for conformational studies of DNA structure dynamics and drug and small molecule interactions.
制备说明
Polymers composed of dG and dC can be difficult to dissolve. The recommended dissolution method for poly(dG) • poly(dC) is to suspend the polymer in a minimum of 15 μl per unit in water or buffer and heat to 50-55 °C for 30 minutes with occasional mixing by inversion.
其他说明
High molecular weight double-stranded homopolymer
One unit will yield an A260 of 1.0 in 1.0 ml of 20 mM sodium phosphate/100 mM NaCl, pH 7.0 (1 cm light path).
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
监管及禁止进口产品
此项目有
Sebastiano Campagna et al.
Inorganic chemistry, 50(21), 10667-10672 (2011-10-01)
Efficient intercalation of a luminescent Ir(III) complex exclusively made of polypyridine ligands in natural and synthetic biopolymers is reported for the first time. The emission of the complex is largely enhanced in the presence of [poly(dA-dT)(2)] and strongly quenched in
M Behe et al.
Proceedings of the National Academy of Sciences of the United States of America, 78(3), 1619-1623 (1981-03-01)
We have compared the behavior in solution of the synthetic polynucleotide poly(dG-m5dC).poly(dG-m5dC) with that of the unmethylated polynucleotide poly(dG-dC).poly(dG-dC). In solutions containing high concentrations of salt, poly(dG-dC).poly(dG-dC) is known to exhibit altered circular dichroic and absorption spectra correlated with formation
Studies of the fluorescence light-up effect of amino-substituted benzo[b]quinolizinium derivatives in the presence of biomacromolecules.
Faulhaber K, Granzhan A, Ihmels H, et al.
Photochemistry and Photobiology, 10, 1535-1545 (2011)
Marta Airoldi et al.
Journal of biomolecular structure & dynamics, 23(4), 465-478 (2005-12-21)
The model polynucleotide poly(dG-dC).poly(dG-dC) (polyGC) was titrated with a strong acid (HCl) in aqueous unbuffered solutions and in the quaternary w/o microemulsion CTAB/n-pentanol/n-hexane/water. The titrations, performed at several concentrations of NaCl in the range 0.005 to 0.600 M, were followed
Effect of the alkaline cations on the stability of the model polynucleotide poly(dG-dC)·poly(dG-dC).
Marta Airoldi et al.
Journal of biomolecular structure & dynamics, 29(3), 585-594 (2011-11-10)
When the model polynucleotide poly(dG-dC)∙poly(dG-dC) [polyGC] is titrated with a strong acid (HCl) in unbuffered aqueous solutions containing the chlorides of the alkali metals in the concentration range 0.010 M-0.600 M, two transitions in the absorbance vs. pH plots are evidenced, characterized
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持