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P3415

3-（2-吡啶二硫）丙酸 N -羟基琥珀酰亚胺酯

Name: 3-（2-吡啶二硫）丙酸 <I> N </I>-羟基琥珀酰亚胺酯
Brand: SIGMA

≥95%, powder

别名:

N-琥珀酰亚胺-3-(2-吡啶二硫代)丙酸酯, SPDP

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关于此项目

经验公式（希尔记法）:

C₁₂H₁₂N₂O₄S₂

化学文摘社编号:

68181-17-9

分子量:

312.36

UNSPSC Code:

12352106

NACRES:

NC.07

PubChem Substance ID:

24898409

EC Number:

269-034-3

Beilstein/REAXYS Number:

1548137

MDL number:

MFCD00009636

Assay:

≥95%

Form:

powder

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Quality Level

200

assay

≥95%

form

powder

reaction suitability

reagent type: cross-linking reagent

mp

84-86 °C (lit.)

solubility

acetone: 50 mg/mL, DMF: soluble

functional group

NHS ester

storage temp.

−20°C

SMILES string

O=C(CCSSC1=NC=CC=C1)ON2C(CCC2=O)=O

InChI

1S/C12H12N2O4S2/c15-10-4-5-11(16)14(10)18-12(17)6-8-19-20-9-3-1-2-7-13-9/h1-3,7H,4-6,8H2

InChI key

JWDFQMWEFLOOED-UHFFFAOYSA-N

General description

3-(2-吡啶基二硫代)丙酸 N-羟基琥珀酰亚胺酯（SPDP）是具有胺和巯基反应性的异源双功能交联剂。通常先在pH 7.5（6.5-8.5）的缓冲条件下通过酰胺键与含有伯胺的分子偶联。在pH 8.0（7.5-8.5）的缓冲条件下通过硫醇-二硫化物交换反应，与含有游离巯基的分子特异性二次偶联。此外，该试剂还可在初次偶联和还原接头后用作受保护的硫醇化试剂。它包含四个原子连接器。

Application

3-（2-吡啶基二硫代）丙酸N-羟基琥珀酰亚胺酯（SPDP）可用于制备酶免疫缀合物和半抗原载体分子偶联物。它已用于抗体缀合和作为蛋白质交联剂。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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全球贸易项目编号

货号	GTIN
P3415-5MG	04061833289914
P3415-25MG	04061834367901
P3415-100MG	04061834367895

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