Merck
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文件

P4060

Sigma-Aldrich

植烷酸

≥96%, mixture of isomers

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别名:
3,7,11,15-四甲基十六碳酸, NSC 108698, 植烷酸
经验公式（希尔记法）:
C20H40O2
CAS号:
14721-66-5
分子量:
312.53
MDL编号:
MFCD00133772
PubChem化学物质编号:
24898502
NACRES:
NA.25

生物来源

synthetic (organic)

质量水平

200

检测方案

≥96%

形式

liquid

官能团

carboxylic acid

脂质类型

saturated FAs

运输

ambient

储存温度

2-8°C

SMILES字符串

CC(C)CCCC(C)CCCC(C)CCCC(C)CC(O)=O

InChI

1S/C20H40O2/c1-16(2)9-6-10-17(3)11-7-12-18(4)13-8-14-19(5)15-20(21)22/h16-19H,6-15H2,1-5H3,(H,21,22)

InChI key

RLCKHJSFHOZMDR-UHFFFAOYSA-N

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象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H315 - H319 - H335

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

10 - Combustible liquids

WGK

WGK 3

个人防护装备

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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Lars I Hellgren
Annals of the New York Academy of Sciences, 1190, 42-49 (2010-04-15)
Phytanic acid is a multibranched fatty acid with reported retinoid X receptor (RXR) and peroxisome proliferator-activated receptor-alpha (PPAR-alpha) agonist activity, which have been suggested to have preventive effects on metabolic dysfunctions. Serum level in man is strongly correlated to the
D M van den Brink et al.
Cellular and molecular life sciences : CMLS, 63(15), 1752-1765 (2006-06-27)
Phytanic acid is a branched-chain fatty acid that accumulates in a variety of metabolic disorders. High levels of phytanic acid found in patients can exceed the millimolar range and lead to severe symptoms. Degradation of phytanic acid takes place by
P P Van Veldhoven et al.
Advances in experimental medicine and biology, 466, 273-281 (2000-03-10)
Synthetic 3-methyl-branched chain fatty acids were used to decipher the breakdown of phytanic acid. Based on results obtained in intact or permeabilized rat hepatocytes, rat liver homogenates or subcellular fractions, a revised alpha-oxidation pathway is proposed which appears to be
Ronald J A Wanders et al.
Biochimica et biophysica acta, 1811(9), 498-507 (2011-06-21)
Phytanic acid (3,7,11,15-tetramethylhexadecanoic acid) is a branched-chain fatty acid which cannot be beta-oxidized due to the presence of the first methyl group at the 3-position. Instead, phytanic acid undergoes alpha-oxidation to produce pristanic acid (2,6,10,14-tetramethylpentadecanoic acid) plus CO(2). Pristanic acid
R J Wanders et al.
Journal of neuropathology and experimental neurology, 60(11), 1021-1031 (2001-11-15)
Refsum disease was first recognized as a distinct disease entity by Sigvald Refsum in the 1940s. The discovery of markedly elevated levels of the branched-chain fatty acid phytanic acid in certain patients marked Refsum disease as a disorder of lipid
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