P4060
植烷酸
≥96%, mixture of isomers
别名:
3,7,11,15-四甲基十六碳酸, NSC 108698, 植烷酸
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关于此项目
经验公式（希尔记法）:
C20H40O2
化学文摘社编号:
分子量:
312.53
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352211
MDL number:
InChI
1S/C20H40O2/c1-16(2)9-6-10-17(3)11-7-12-18(4)13-8-14-19(5)15-20(21)22/h16-19H,6-15H2,1-5H3,(H,21,22)
SMILES string
CC(C)CCCC(C)CCCC(C)CCCC(C)CC(O)=O
InChI key
RLCKHJSFHOZMDR-UHFFFAOYSA-N
biological source
synthetic (organic)
assay
≥96%
form
liquid
functional group
carboxylic acid
lipid type
saturated FAs
shipped in
ambient
storage temp.
2-8°C
Quality Level
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
10 - Combustible liquids
wgk
WGK 3
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
D M van den Brink et al.
Cellular and molecular life sciences : CMLS, 63(15), 1752-1765 (2006-06-27)
Phytanic acid is a branched-chain fatty acid that accumulates in a variety of metabolic disorders. High levels of phytanic acid found in patients can exceed the millimolar range and lead to severe symptoms. Degradation of phytanic acid takes place by
Lars I Hellgren
Annals of the New York Academy of Sciences, 1190, 42-49 (2010-04-15)
Phytanic acid is a multibranched fatty acid with reported retinoid X receptor (RXR) and peroxisome proliferator-activated receptor-alpha (PPAR-alpha) agonist activity, which have been suggested to have preventive effects on metabolic dysfunctions. Serum level in man is strongly correlated to the
N M Verhoeven et al.
Journal of inherited metabolic disease, 21(7), 697-728 (1998-11-20)
The branched-chain fatty acid phytanic acid is a constituent of the diet, present in diary products, meat and fish. Degradation of this fatty acid in the human body is preceded by activation to phytanoyl-CoA and starts with one cycle of
A W Zomer et al.
Journal of lipid research, 41(11), 1801-1807 (2000-11-04)
Phytanic acid and pristanic acid are branched-chain fatty acids, present at micromolar concentrations in the plasma of healthy individuals. Here we show that both phytanic acid and pristanic acid activate the peroxisome proliferator-activated receptor alpha (PPARalpha) in a concentration-dependent manner.
R J Wanders et al.
Journal of neuropathology and experimental neurology, 60(11), 1021-1031 (2001-11-15)
Refsum disease was first recognized as a distinct disease entity by Sigvald Refsum in the 1940s. The discovery of markedly elevated levels of the branched-chain fatty acid phytanic acid in certain patients marked Refsum disease as a disorder of lipid
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